Pernell Roberts
"Trapper" John McIntyre (151 eps)
Gregory Harrison
George Alonzo 'Gonzo' Gates (151 eps)
Charles Siebert
Stanley Riverside III (151 eps)
Brian Stokes Mitchell
Justin "Jackpot" Jackson (151 eps)
Christopher Norris
Gloria Brancusi (132 eps)
Madge Sinclair
Ernestine Shoop, R. N. (129 eps)
Simon Scott
Arnold Slocum (110 eps)
Timothy Busfield
J.T. McIntyre Jr. (42 eps)
Mary McCarty
Clara 'Starch' Willoughby, R. N. (22 eps)
Lorna Luft
Libby Kegler (19 eps)
Kip Gilman
Jacob Christmas (19 eps)
Janis Paige
Catherine Hackett (19 eps)
Jessica Walter
Melanie Townsend McIntyre (10 eps)
Robin Ignico
Andrea (4 eps)
Jerry Ayres
Policeman #1 / Security Guard (3 eps)
Sheila Larken
Eleanor Buxton (2 eps)
Paul Bryar
Homer (2 eps)
Pamela Dunlap
Woman (2 eps)
William Smith
Tugwell (1 eps)
Nita Talbot
Mrs. Englehart (1 eps)
Stacey Nelkin
Kim (1 eps)
James Gleason
Jeff Phillips (1 eps)
Daniel Keough
Ranger (1 eps)
Jennifer Jason Leigh
Karen McCall (1 eps)
Marki Bey
Elva (1 eps)
Ann Dusenberry
Maggie Nolan (1 eps)
Frank Coppola
Anesthesiologist (1 eps)
James McKenna
Young Patient (1 eps)
Anne Bruner
Woman (1 eps)
Joan Sweeny
Margaret/Peggy (1 eps)
Carla Portillo Whitby
Emita (1 eps)
Lew Saunders
Terry Todd (1 eps)
Rhonda Hopkins
Ms. Tanner (1 eps)
Helen Rubio
Mrs. Rivera (1 eps)
Geraldine Fitzgerald
Bag lady (1 eps)