Zach Braff
John 'J.D.' Dorian (25 eps)
Donald Faison
Christopher Turk (25 eps)
John C. McGinley
Perry Cox (25 eps)
Sarah Chalke
Elliot Reid (25 eps)
Judy Reyes
Carla Espinosa (25 eps)
Ken Jenkins
Bob Kelso (25 eps)
Neil Flynn
Janitor (25 eps)
Robert Maschio
Todd (18 eps)
Sam Lloyd
Ted Buckland (16 eps)
Christa Miller
Jordan Sullivan (13 eps)
Heather Graham
Dr. Molly Clock (9 eps)
Aloma Wright
Laverne Roberts (8 eps)
Johnny Kastl
Doug Murphy (8 eps)
Michael Hobert
Lonnie (7 eps)
Chrystee Pharris
Kylie (5 eps)
Josh Randall
Jake (3 eps)
Amy Rilling
Nurse (3 eps)
Frank Encarnacao
Dr. Mickhead (3 eps)
Phill Lewis
Hooch (3 eps)
Martin Klebba
Randall (3 eps)
Richard Kind
Mr. Corman (2 eps)
Julianna Margulies
Neena (2 eps)
Marshall Manesh
Dr. Akbar (2 eps)
Cullen Douglas
Two O'Clock Man (2 eps)
Monica Allgeier
Nurse Tisdale (2 eps)
Mike Schwartz
Delivery Guy (2 eps)
Tom Cavanagh
Dan Dorian (2 eps)
Joe Rose
Troy (2 eps)
Meredith Roberts Quill
Kathy (2 eps)
Biff Yeager
Dr. Walch (1 eps)
Ed McMahon
Ed McMahon (1 eps)
Michael Copon
Pedro (1 eps)
Colin Farrell
Billy (1 eps)
Ken Lerner
Mr. James (1 eps)
Loren Lester
Vet (1 eps)
Jon Polito
Mr. Summers (1 eps)
John Bennett Perry
Harrison (1 eps)
Chris Hogan
Mr. Gerst (1 eps)
Mike Weinberg
Tyler (1 eps)
Matthew Perry
Murray (1 eps)
Mary Mouser
Girl (1 eps)
Tim Conlon
Dean (1 eps)
Common
Common (1 eps)
Michael Boatman
Ron (1 eps)
Tara Reid
Danni (1 eps)
Ed Brigadier
Barber (1 eps)
Femi Emiola
Young Woman (1 eps)
Clay Aiken
Kenny (1 eps)
Chuck Woolery
Chuck Woolery (1 eps)
Zach Mills
Young J.D. (1 eps)
Sarah Ramos
Lindsay (1 eps)
Lindsay Hollister
Nell (1 eps)
Jim Hanks
Dr. Turner (1 eps)
Christopher Darga
Homeless Steve (1 eps)
Dayo Ade
Mr. Hovey (1 eps)
Jeremy Howard
Fat Frank (1 eps)
Michael Bunin
Jerry (1 eps)
James Michael Tyler
Therapist (1 eps)
Timothy Davis-Reed
Interviewer (1 eps)
Trev Broudy
Doctor (1 eps)
Ellen Albertini Dow
Betty (1 eps)
Myra Turley
Woman (1 eps)
Molly Shannon
Denise Lemmon (1 eps)
Erin Carufel
Woman in Tub (uncredited) (1 eps)
Cynthia Frost
Mrs. Grodberg (1 eps)
Jordi Caballero
Massimo (1 eps)
Michael Alaimo
Mr. Radford (1 eps)
Masi Oka
Franklyn (1 eps)
Bart Sumner
Mr. Blass (1 eps)
Harriett S. Miller
Elderly Woman (1 eps)
John Brady
Mr. Silka (1 eps)
Andrew Herman
Mr. Roman (1 eps)
Herman Poppe
Mr. Porter (1 eps)
Jennie Ventriss
Pat (1 eps)
Chuck Lacey
Odd Doctor (1 eps)
Larkin Campbell
Guy (1 eps)
Bronwen Booth
Miss Myers (1 eps)
Jody Carter
Mrs. Covello (1 eps)
Garrett Donovan
Councilman Donovan (1 eps)
Brogan Roche
Dr. Lemmon (1 eps)
Steven Montfort
Softball Player (1 eps)
Jack Shearer
Aaron Simon (1 eps)
Carol Herman
Mrs. Carter (1 eps)
Kevin Lowe
Mr. Daniels (1 eps)
Joseph Limbaugh
Guy (1 eps)
Ted Rogers
Mr. Burski (1 eps)
Connor Patterson
Sammy (1 eps)
Wendy Schenker
Mrs. MacCalla (1 eps)
Jason-Shane Scott
Mike (1 eps)
Sylvia MacCalla
Prostitute (1 eps)
Ross Mackenzie
Patient (1 eps)
Gabrielle Allan
Glenda (1 eps)
Tiffany Cade
Mary (1 eps)
Mercy Malick
Contortionist (1 eps)
Yosemite Stokesberry
Hell's Angel (1 eps)
Jeff Witzke
Father (1 eps)
Jay Malack
Shinski (1 eps)
Andrew Friedman
EMT (1 eps)
Amy Ferguson
Girl (1 eps)
William Bassett
Patient (1 eps)
Terrence Beasor
Man in Bed (1 eps)
Al Checco
Man in Bed (1 eps)
Tacey Adams
Woman (1 eps)
Dutch Hofstetter
Young Dr. Cox (1 eps)
Alysia Joy Powell
Karen (1 eps)
David Pressman
Mickey (1 eps)
Ralph Cole Jr.
Glen (1 eps)
Bayard Crawley
Dave (1 eps)
Barry Cutler
Brett (1 eps)
Brian Kaiser
Emcee (1 eps)
Tony Perry
Old Murray (1 eps)
Adam Bitterman
Worker (1 eps)
Colin Bain
Steve (1 eps)
Adam Zolotin
Reuben (1 eps)
Matt Kaminsky
Mr. Milligan (1 eps)
Randy Crowder
Patient (1 eps)
Kareem Ferguson
Waiter (1 eps)
Wells Rosales
Student (1 eps)
Linda Porter
Old Woman (1 eps)
Shanola Hampton
Woman (1 eps)
Reggie Currelley
Man (1 eps)
Lindsey Stoddart
Nurse Haltson (1 eps)
Natalie Farrey
Daisy (1 eps)
Paige Peterson
Surgical Nurse (1 eps)
Matthew Pohlson
Patient (1 eps)
Marc D. Wilson
James (1 eps)
Takayo Fischer
Mrs. Cheng (1 eps)
Gregory Hinton
Bouncer (1 eps)
Gary Rubenstein
Patient (1 eps)
Deonte Gordon
Figsack (1 eps)
Jennifer Bowman
Nurse Birdie (1 eps)
Ian Kerr
Mr. Peeps (voice) (1 eps)
Tim Haldeman
Mr. Warner (1 eps)
Cody Estes
Young J.D. (1 eps)
Michael Cotter
Michael (1 eps)
Mary-Margaret Lewis
Woman (1 eps)
Ian Vogt
Father (1 eps)
Piolet Thompkins
Roland (1 eps)
Stephanie Brown
Jenny (1 eps)
Whitney Rydbeck
Dennis (1 eps)
Sue Ozeran
Lady (1 eps)
Scott Damian
Man (1 eps)
Fred Stoller
Mr. Hoffner (1 eps)
Janelle Marra
Nurse (1 eps)
Larry Marko
Mr. Gilmore (1 eps)
Hira Ambrosino
Realtor (1 eps)
John Balma
Owner (1 eps)
Steve Bolton
Crazy Guy (1 eps)
Elton Laron
Black Guy (1 eps)
Brandon Waters
Young Janitor (1 eps)
Stuart McLean
Dr. Gold (1 eps)
Madison R. Wells
Karen (1 eps)
Brian Oerly
Angry Neighbor (1 eps)
Kattia Ortiz
Nurse (1 eps)
Ming Lo
Dr. Kim (1 eps)
Geoff Stevenson
Dr. Beardface (1 eps)
Charles Rahi Chun
Dr. Wen (1 eps)
Bob Clendenin
Dr. Zeltzer (1 eps)
Kathryn Joosten
Mrs. Tanner (1 eps)
George Miserlis
Crispin (1 eps)
Philip McNiven
Roy (1 eps)
Paul F. Perry
Randall (1 eps)
Jill Tracy
Elaine (1 eps)