Johnny Knoxville
Luke Duke
Seann William Scott
Bo Duke
Jessica Simpson
Daisy Duke
Willie Nelson
Uncle Jesse Duke
Burt Reynolds
Jefferson Davis 'Boss' Hogg
M.C. Gainey
Sheriff Rosco P. Coltrane
James Roday Rodriguez
Billy Prickett
David Koechner
Cooter Davenport
Michael Weston
Deputy Enos Strate
Nikki Griffin
Katie Johnson
Alice Greczyn
Laurie Pullman
Joe Don Baker
Governor Jim Applewhite
Lynda Carter
Pauline
Kevin Heffernan
Sheev
Steve Lemme
Jimmy
Michael Roof
Dil Driscoll
Jack Polick
Deputy Cletus Hogg
Jacqui Maxwell
Annette
Charlie Finn
Royce
Therial 'Houseman' DeClouet
Judge Locke Randolph
Jim Cody Williams
Security Guard Chip
Wayne Douglas Morgan
Prisoner
Junior Brown
The Balladeer (voice)
Andrew Prine
Angry Man
David Leitch
Puncher
Christina Dare
Sorority Girl
Jay Chandrasekhar
Campus Cop #1
Erik Stolhanske
Campus Cop #2
A.J. Foyt IV
Race Car Driver #1
Dolan Wilson
Local #2
Heather Hemmens
Girl #1
Mitch Braswell
Out of Towner #1
Rusty Tennant
Local #1