Eric McCormack
Will Truman (24 eps)
Debra Messing
Grace Adler (24 eps)
Sean Hayes
Jack McFarland (24 eps)
Megan Mullally
Karen Walker (24 eps)
Bobby Cannavale
Vince D'Angelo (7 eps)
John Ducey
Jamie (4 eps)
Mark Harelik
Tim (3 eps)
Jeff Goldblum
Scott Woolley (3 eps)
Edward Burns
Nick (3 eps)
Josh Keaton
Salvatore (2 eps)
Alec Baldwin
Malcolm Widmark (2 eps)
Harry Connick Jr.
Leo Markus (2 eps)
Jamie Kaler
Gary (2 eps)
Jamie-Lynn Sigler
Ro (2 eps)
Lee Garlington
Annette (2 eps)
Blythe Danner
Marilyn Truman (2 eps)
Bridget Flanery
Viv Cassidy (2 eps)
Robert Costanzo
Paul (2 eps)
Eric Stoltz
Tom Cassidy (2 eps)
Leslie Jordan
Beverley Leslie (2 eps)
Mathew Botuchis
Dave (2 eps)
Sam Pancake
Jimmy (2 eps)
Lee Majors
Burt Wolfe (1 eps)
Steve Ryan
Lieutenant (1 eps)
Stephen Tobolowsky
Ned Weathers (1 eps)
Erinn Hayes
Katherine Fallon (1 eps)
Kristin Davis
Nadine (1 eps)
Victor Garber
Peter Bovington (1 eps)
Ashley Edner
Ruby (1 eps)
Patti LuPone
Herself (1 eps)
Chita Rivera
Lenore (1 eps)
Luke Perry
Aaron (1 eps)
Stuart Townsend
Edward - Pastry Chef (1 eps)
Eric Allan Kramer
Barry (1 eps)
Phil Morris
Dr. Norman (1 eps)
Stacy Keach
Wendell Schacter (1 eps)
Chris Gartin
Desmond (1 eps)
Janet Jackson
Janet Jackson (1 eps)
Patrick Fabian
Alan (1 eps)
Kari Lizer
Connie (1 eps)
Buck Henry
Leonard (1 eps)
Trev Broudy
Waiter (1 eps)
Michele Lee
Lucille (1 eps)
Sharon Stone
Dr. Georgia Keller (1 eps)
Leigh-Allyn Baker
Ellen (1 eps)
Tim Bagley
Larry (1 eps)
Alan Arkin
Martin Adler (1 eps)
Larry Poindexter
Dan Fallon (1 eps)
Karl T. Wright
Wayne (1 eps)
Rip Taylor
Self (1 eps)
Lily Tomlin
Margot (1 eps)
Michael Merton
Maitre D' (1 eps)
Seth Green
Randall (1 eps)
Emily Rutherfurd
Joanne (1 eps)
Will Arnett
Artemus Johnson (1 eps)
Roscoe Lee Browne
Linus (1 eps)
Hallee Hirsh
Olivia Walker (1 eps)
Will Schaub
Dennis (1 eps)
Joyce Guy
Lynette (1 eps)
Erin Hershey Presley
Nicole (1 eps)
Dmitri S. Boudrine
Man (1 eps)
Debbie Reynolds
Bobbi Adler (1 eps)
Rachel Quaintance
Roz (1 eps)
Molly Shannon
Val Bassett (1 eps)
Jerry Levine
Joe (1 eps)
Jennifer Lopez
Jennifer Lopez (1 eps)
Eileen Fogarty
Hostess (1 eps)
Jason Landau
Passenger (1 eps)
Andrew Ableson
Choreographer (1 eps)
Julie Pop
Pat (1 eps)
Marcy Goldman
Judy (1 eps)
Jodi Fleisher
Woman (1 eps)
Kevin Brief
Ralph (1 eps)
Markus Hamilton
Colin (1 eps)
Barry Karas
Man in Bookstore (1 eps)
John P. Connolly
Gardener (1 eps)
Christian S. Anderson
Man (1 eps)
Deborah Carson
Margaret (1 eps)
Marissa Matrone
Aunt Angie (1 eps)
Benjamin Sprunger
Matt (1 eps)
Gina Morelli
Grandma (1 eps)
Cody Weiant
Maisie (1 eps)
Helen Geller
Fiona (1 eps)
Paolo Presta
Mark (1 eps)
Eric Cazenave
Clive (1 eps)