Jharrel Jerome
Korey Wise (4 eps)
Ethan Herisse
Young Yusef Salaam (4 eps)
Marquis Rodriguez
Young Raymond Santana Jr. (4 eps)
Asante Blackk
Young Kevin Richardson (4 eps)
Caleel Harris
Young Antron McCray (4 eps)
Marsha Stephanie Blake
Linda McCray (4 eps)
Michael Kenneth Williams
Bobby McCray (4 eps)
John Leguizamo
Raymond Santana Sr. (4 eps)
Aunjanue Ellis-Taylor
Sharonne Salaam (4 eps)
Niecy Nash-Betts
Deloris Wise (4 eps)
Vera Farmiga
Elizabeth Lederer (4 eps)
Kylie Bunbury
Angie Richardson (4 eps)
Suzzanne Douglas
Grace Cuffee (4 eps)
Len Cariou
DA Robert Morgenthau (3 eps)
William Sadler
Detective Michael Sheehan (3 eps)
Alexandra Templer
Trisha Meili (3 eps)
Adepero Oduye
Nomsa Brath (3 eps)
Omar J. Dorsey
Elombre Brath (3 eps)
Joshua Jackson
Mickey Joseph (3 eps)
Felicity Huffman
Linda Fairstein (3 eps)
Famke Janssen
Nancy Ryan (2 eps)
Christopher Jackson
Peter Rivera (2 eps)
Blair Underwood
Bobby Burns (2 eps)
Chukwudi Iwuji
Colin Moore (2 eps)
Chris Chalk
Yusef Salaam (Adult) (2 eps)
Freddy Miyares
Raymond Santana Jr. (Adult) (2 eps)
Jovan Adepo
Antron McCray (Adult) (2 eps)
Justin Cunningham
Kevin Richardson (Adult) (2 eps)
Gary Perez
Manuel Santana (2 eps)
Aurora Perrineau
Tanya (2 eps)
Dascha Polanco
Elena (2 eps)
Storm Reid
Lisa (2 eps)
Elijah Richardson
Al Morris (2 eps)
Caroline Hewitt
Local News Reporter (2 eps)
Rosa Arredondo
Dr. Fraine (1 eps)
Bruce MacVittie
Detective Hartigan (1 eps)
Ariel Shafir
Detective Jaffer (1 eps)
Patrick Gallo
Detective Taglioni (1 eps)
Blake DeLong
Detective Nugent (1 eps)
Jayce Bartok
Detective Hildebrandt (1 eps)
Frank Pando
Detective Gonzales (1 eps)
Tom Lipinski
Detective Farrell (1 eps)
Danny Wolohan
Detective McCabe (1 eps)
Ty Jones
Officer Reynolds (1 eps)
Michael C. Brennan
Officer Powers (1 eps)
Maxwell Whittington-Cooper
Precinct Clerk Billy (1 eps)
Brett Gray
Clarence (1 eps)
Isis King
Norman (Denise) Wise (1 eps)
Reece Noi
Matias Reyes (1 eps)
Joaquina Kalukango
Adelle (1 eps)
Taylor Selé
Chris Black (1 eps)
Ivory Aquino
Mrs. Baqri (1 eps)