Ashton Kutcher
Walden Schmidt (24 eps)
Jon Cryer
Alan Harper (24 eps)
Angus T. Jones
Jake Harper (24 eps)
Conchata Ferrell
Berta (24 eps)
Holland Taylor
Evelyn Harper (24 eps)
Marin Hinkle
Judith Harper (24 eps)
Sophie Winkleman
Zoey (12 eps)
Courtney Thorne-Smith
Lyndsey Mackelroy (12 eps)
Judy Greer
Bridget Schmidt/Danny (9 eps)
Graham Patrick Martin
Eldridge Mackelroy (8 eps)
Talyan Wright
Ava (4 eps)
Ryan Stiles
Herb (4 eps)
Macey Cruthird
Megan (3 eps)
Melanie Lynskey
Rose (2 eps)
Mimi Rogers
Robin Schmidt (2 eps)
Vernee Watson-Johnson
Nurse Lorna (2 eps)
Matthew Marsden
Nigel (2 eps)
Georgia Engel
Jean (2 eps)
Patton Oswalt
Billy Stanhope (2 eps)
Rebecca McFarland
Leanne (2 eps)
Jenny McCarthy-Wahlberg
Courtney (2 eps)
Robert Clotworthy
Pilot (voice) (2 eps)
Jennifer Taylor
Chelsea (1 eps)
Jenna Elfman
Frankie (1 eps)
Jeri Ryan
Sherri (1 eps)
Katherine LaNasa
Lydia (1 eps)
Joel Murray
Doug (1 eps)
John Stamos
Prospective House Buyer (1 eps)
Thomas Gibson
Greg (1 eps)
Angelique Cabral
Shannon (1 eps)
Alexis Krause
Kelly (1 eps)
Stephanie Jacobsen
Penelope (1 eps)
Nicole J. Butler
Mother (1 eps)
Grady Lee Richmond
Elmer (1 eps)
Nikki Novak
Naomi (1 eps)
Nicholas Gonzalez
Baker (1 eps)
Katie Stegeman
Malibu Volleyball Player (1 eps)
Taylor Cole
Melanie Laughlin (1 eps)
Joe Manganiello
Alex (1 eps)
Monika Smith
Kiki (1 eps)
Amanda Schull
Alicia (1 eps)
Gary Busey
Gary Busey (1 eps)
Zaid Farid
James (1 eps)
Michael Bailey Smith
Dave (1 eps)
Nicole Steinwedell
Veronica Hastings (1 eps)
Brian Keith Russell
Thomas (1 eps)
Jonathan Banks
Sid (1 eps)
Jane Carr
Sharon (1 eps)
Jim Piddock
Edward (1 eps)
John Pirruccello
Policeman (voice) (1 eps)
Chuck Lacey
Martin (1 eps)
Michael Medico
Bartender (1 eps)
Travis Van Winkle
Dylan (1 eps)
Sonia Jackson
Andrea (1 eps)
Sara Erikson
Jennifer (1 eps)
Hira Ambrosino
Kim (1 eps)
Kathy Bates
Charlie Harper (1 eps)
Brian Stepanek
Arthur (1 eps)
Eddie Shin
Dr. Kim (1 eps)
Caitlin Harris
Lauren (1 eps)
Christina Scherer
Jenny (1 eps)
Abbie Cobb
Gabby (1 eps)
Chase Austin
Slacker #1 (1 eps)
Jason Alexander
Dr. Goodman (1 eps)
Ryan Heinke
Slacker #2 (1 eps)
Alem Brhan Sapp
Drill Sergeant (1 eps)
Richard Whiten
Sergeant Preston (1 eps)
Abby Walker
Lady #2 (1 eps)
Martin Mull
Russell (1 eps)
Jeff Staron
Barista (1 eps)
Denise Richards
Lisa (1 eps)
Tricia Helfer
Gail (1 eps)
Shon Little
Cashier (1 eps)
Jane Lynch
Dr. Linda Freeman (1 eps)
Jodi Lyn O'Keefe
Isabella (1 eps)
Liz Vassey
Michelle (1 eps)
Amira Elliby
Six year-old girl (1 eps)
Emile Ballard
Toddler (1 eps)
Karen Y. McClain
Chrissy (1 eps)
Jacqueline Lord
Lady #1 (1 eps)
Alicia Hannah
Lotus (1 eps)
Emmanuelle Vaugier
Mia (1 eps)
Missi Pyle
Miss Pasternak (1 eps)