Martin Sheen
President Josiah Bartlet (22 eps)
Allison Janney
C.J. Cregg (22 eps)
Richard Schiff
Toby Ziegler (22 eps)
John Spencer
Leo McGarry (22 eps)
Bradley Whitford
Josh Lyman (22 eps)
Dulé Hill
Charlie Young (22 eps)
Joshua Malina
Will Bailey (22 eps)
Janel Moloney
Donna Moss (22 eps)
Timothy Davis-Reed
Mark O'Donnell (22 eps)
Stockard Channing
Abbey Bartlet (22 eps)
NiCole Robinson
Margaret Hooper (13 eps)
Lily Tomlin
Deborah Fiderer (9 eps)
Gary Cole
Vice President Bob Russell (9 eps)
Jesse Bradford
Ryan Pierce (9 eps)
Melissa Marsala
Rina (6 eps)
Ron Canada
Under Secretary of State Theodore Barrow (6 eps)
Steve Ryan
Miles Hutchinson (5 eps)
Michael Hyatt
Angela Blake (5 eps)
Terry O'Quinn
General Nicholas Alexander (5 eps)
Steven Culp
Speaker of the House Jeff Haffley (5 eps)
Mary-Louise Parker
Amy Gardner (4 eps)
Renée Estevez
Nancy (4 eps)
Elisabeth Moss
Zoey Bartlet (4 eps)
John Amos
Percy Fitzwallace (4 eps)
Nina Siemaszko
Ellie Bartlet (3 eps)
Anna Deavere Smith
Nancy McNally (3 eps)
Sam Robards
Greg Brock (3 eps)
Ryan Cutrona
CIA Director George Rollie (3 eps)
Jay Mohr
Taylor Reid (3 eps)
Kathleen York
Andrea Wyatt (2 eps)
Michael O'Neill
Ron Butterfield (2 eps)
Rebecca Avery
Anna - Reporter #1 / Co-Anchor / Aide / Reporter #3 (2 eps)
Geoff Pierson
Senator Tripplehorn (2 eps)
Steven Eckholdt
Doug Westin (2 eps)
Clark Gregg
FBI Special Agent Michael Casper (2 eps)
Melissa Fitzgerald
Carol Fitzpatrick (2 eps)
Jason Isaacs
Colin Ayres (2 eps)
Hira Ambrosino
White House Correspondent (2 eps)
Joyce Guy
Reporter Charlayne (2 eps)
Milo O’Shea
Chief Justice Roy Ashland (2 eps)
Brian Kerwin
Ben Dryer (2 eps)
Wilson Cruz
Jack Sosa (2 eps)
Will Lyman
Narrator (voice) (1 eps)
Timothy Busfield
Danny Concannon (1 eps)
Zeljko Ivanek
Steve Atwood (1 eps)
James Cromwell
President D. Wire Newman (1 eps)
Stephen Tobolowsky
Dr. Max Milkman (1 eps)
Allison Smith
Mallory O'Brien (1 eps)
Diana Douglas
Libby Lassiter (1 eps)
Maz Jobrani
Prince Bitar (1 eps)
Bellamy Young
MaryLou Meriwether (1 eps)
Gabrielle Union
Meeshel Anders (1 eps)
John Goodman
Glenallen Walken (1 eps)
Tim Matheson
John Hoynes (1 eps)
Annabeth Gish
Elizabeth Bartlet Westin (1 eps)
Thomas Kopache
Bob Slatterly (1 eps)
William Devane
Secretary of State Lewis Berryhill (1 eps)
Joanne McGee
Wife (1 eps)
Matthew Perry
Joe Quincy (1 eps)
Benjamin Brown
Mike (1 eps)
Tony Lee
Jai Yung Ahn - Pianist (1 eps)
Christopher Cousins
Rep. Theo (1 eps)
Tom Skerritt
Senator Chris Carrick (1 eps)
Erinn Hayes
Laura (1 eps)
Bryan Callen
Louis Slater (1 eps)
Maree Cheatham
Governor Wade (1 eps)
Steven Anderson
Daniel Rubin (1 eps)
Nick Searcy
Nate Singer (1 eps)
Jim Moret
Newscaster (1 eps)
Lauren Stamile
C.J.'S Aide (1 eps)
Obi Ndefo
Donald (1 eps)
Brandon Barash
Bret (1 eps)
Armin Mueller-Stahl
Israeli Prime Minister Efraim 'Eli' Zahavy (1 eps)
Mark Moses
Donald Richter (1 eps)
Dylan Baker
Attorney General Alan Fisk (1 eps)
Bruno Gunn
Agent Len (1 eps)
Josef Sommer
Steve Gaines (1 eps)
Kate Burton
Sarah Brainerd (1 eps)
Michael Nouri
Roy Turner (1 eps)
Scott Allan Campbell
Grey Polk (1 eps)
Joaquim de Almeida
Carlos Carrio (1 eps)
Natalija Nogulich
Israeli Ambassador Shira Galit (1 eps)
Christina Chang
Alex Moreau (1 eps)
Christopher Maher
Iranian Ambassador (1 eps)
Philip Baker Hall
Senator Matt Hunt (1 eps)
Endre Hules
Maitre D' (1 eps)
Peter James Smith
Ed (1 eps)
Gerald McRaney
USAF Gen. Alan Adamle (1 eps)
Jeffrey DeMunn
Kenneth Sean 'Ken' O'Neal (1 eps)
James Pickens Jr.
Mayor (1 eps)
Kenneth Kimmins
Gen. Stanley (1 eps)
Glenn Close
Chief Justice Evelyn Baker Lang (1 eps)
William Fichtner
Justice Christopher Mulready (1 eps)
Mitchell Ryan
Senator Roland Pierce (1 eps)
Albie Selznick
Documentarian (1 eps)
Joseph Vassallo
Renato Mannari (1 eps)
Brian Poth
Eric Schaeffer (1 eps)
Reed Diamond
Dr. Mike Gordon (1 eps)
Carlos Gómez
Admiral McGill (1 eps)
Anna Holbrook
Sally O'Neal (1 eps)
Allan Kolman
Mr. Thomas (1 eps)
Kevin Clash
Elmo (voice) (1 eps)
Carmen Osbahr
Rosita (1 eps)
Joey Mazzarino
Muppet Doctor (1 eps)
John Lafayette
Dr. Louis Foy (1 eps)
Frank Ashmore
Congressman Chris Finn (1 eps)
Ron Dean
Tom Broderick (1 eps)
Michael Mantell
Shelly Lukens (1 eps)
Deirdre Lovejoy
Lisa Wolfe (1 eps)
Michael Gaston
Eric Hayden (1 eps)
Cherry Jones
Barbara Layton (1 eps)
David Castellani
Reporter (1 eps)