Doc Hammer
Dr. Girlfriend / Henchman 21 (voice) (8 eps)
Christopher McCulloch
Hank Venture / The Monarch (voice) (8 eps)
Patrick Warburton
Brock Samson (voice) (8 eps)
James Urbaniak
Dr. Venture (voice) (8 eps)
Michael Sinterniklaas
Dean Venture (voice) (8 eps)
Gillian Jacobs
Marsha Backwood (voice) (1 eps)
Kevin Conroy
Captain Sunshine (voice) (1 eps)
Steven Rattazzi
Dr. Orpheus (voice) (1 eps)