Buster Jones
James 'Twiggy' Sanders / Spaghetti Man (voice) (13 eps)
Scatman Crothers
Nate Branch / Liquid Man (voice) (13 eps)
Adam Wade
Louis 'Sweet Lou' Dunbar / Gizmo (voice) (13 eps)
Johnny Williams
Hubert 'Geese' Ausbie / Multi Man (voice) (13 eps)
Stu Gilliam
Freddie 'Curly' Neal / Super Sphere (voice) (13 eps)
Frank Welker
Crime Globe (voice) (13 eps)
Michael Rye
Narrator (voice) (13 eps)