Dan Castellaneta
Homer Simpson / Abe Simpson / Barney Gumble / Krusty (voice) (23 eps)
Julie Kavner
Marge Simpson / Patty Bouvier / Selma Bouvier (voice) (23 eps)
Nancy Cartwright
Bart Simpson / Nelson Muntz / Ralph Wiggum (voice) (23 eps)
Yeardley Smith
Lisa Simpson (voice) (23 eps)
Hank Azaria
Moe Szyslak / Chief Wiggum / Apu / Comic Book Guy / Carl (voice) (23 eps)
Harry Shearer
Ned Flanders / Mr. Burns / Smithers / Skinner / Lenny (voice) (23 eps)
Jon Lovitz
Artie Ziff / Llewellyn Sinclair / other minor characters. (4 eps)
J.K. Simmons
Victor Kleskow (voice) (2 eps)
Awkwafina
Carmen (voice) (2 eps)
Gal Gadot
Gal Gadot (voice) (1 eps)
Ken Jeong
Korean Monks (voice) (1 eps)
George Segal
Nick (voice) (1 eps)
H. Jon Benjamin
Bob Belcher (voice) (1 eps)
Dan Mintz
Tina Belcher (voice) (1 eps)
Kristen Schaal
Louise Belcher (voice) (1 eps)
RuPaul
Queen Chante (voice) (1 eps)
Scott Thompson
Grady (voice) (1 eps)
Jane Lynch
Jeanie (voice) (1 eps)
Guillermo del Toro
Guillermo del Toro (voice) (1 eps)
Wallace Shawn
Wallace the Hernia (voice) (1 eps)
Nicole Byer
Erica (voice) (1 eps)
Dave Matthews
Lloyd (voice) (1 eps)
Will Forte
King Toot (voice) (1 eps)
Illeana Douglas
New age clerk (voice) (1 eps)
Jenny Slate
Piper Paisley (voice) (1 eps)
Chelsea Peretti
Lauren (voice) (1 eps)
Werner Herzog
Walter Hotenhoffer (voice) (1 eps)
Pete Holmes
Bode Wright (voice) (1 eps)
Jackie Mason
Hyman Krustofsky (voice) (1 eps)
Natasha Lyonne
Sophie (voice) (1 eps)
Maggie Roswell
Maude Flanders (voice) (1 eps)
Lucas Meyer
Justin Trudeau (voice) (1 eps)
John Roberts
Linda Belcher (voice) (1 eps)
Raja Gemini
Raja (1 eps)
Billy Eichner
Billy (voice) (1 eps)
Peter Serafinowicz
Corporate CEO (voice) (1 eps)