Cathy Cavadini
Blossom (voice) (136 eps)
Tara Strong
Bubbles (voice) (136 eps)
Elizabeth Daily
Buttercup (voice) (136 eps)
Tom Kenny
Mayor / Snake / Lil' Arturo / Narrator (voice) (136 eps)
Tom Kane
Professor Utonium / Him / Talking Dog (voice) (136 eps)
Roger L. Jackson
Mojo Jojo (voice) (136 eps)
Jennifer Martin
Ms. Sara Bellum (voice) (136 eps)
Jennifer Hale
Ms. Keane / Princess Morbucks / Sedusa (voice) (136 eps)
Jim Cummings
Fuzzy Lumpkins (voice) (136 eps)
Jeff Bennett
Ace / Grubber / Big Billy (voice) (136 eps)
Chuck McCann
The Amoeba Boys (voice) (136 eps)
Julie Nathanson
Science Teacher / Schoolgirl #1 / Young Ms. Bellum (voice) (2 eps)
Candi Milo
Cleaning Woman (voice) (2 eps)
Phil LaMarr
Bouncer / Guvn'r / Big John / Peses Bill (voice) (2 eps)
Phyllis Diller
Mask Scara (voice) (1 eps)
Christine Cavanaugh
Bunny (voice) (1 eps)
June Foray
Madame Argentina (voice) (1 eps)
Greg Eagles
Sandman (voice) (1 eps)
Mark Hamill
Criminal / Cop #1 (voice) (1 eps)
Don Shank
Naked Guy / Snotty Bank Teller / Man #3 (voice) (1 eps)
John DiMaggio
Captain Crack McGraigen (voice) (1 eps)
Dee Bradley Baker
Parrot / Reginald (voice) (1 eps)