Seth MacFarlane
Capt. Ed Mercer (14 eps)
Adrianne Palicki
Cmdr. Kelly Grayson (14 eps)
Penny Johnson Jerald
Dr. Claire Finn (14 eps)
Scott Grimes
Lt. Gordon Malloy (14 eps)
Peter Macon
Lt. Cmdr. Bortus (14 eps)
Jessica Szohr
Talla Keyali (14 eps)
J. Lee
John LaMarr (14 eps)
Mark Jackson
Isaac (14 eps)
Norm Macdonald
Yaphit (voice) (8 eps)
Blesson Yates
Topa (7 eps)
BJ Tanner
Marcus Finn (5 eps)
Kai Wener
Ty Finn (5 eps)
Kyra Santoro
Ensign Turco (3 eps)
Rachael MacFarlane
Computer Voice (voice) (3 eps)
Ted Danson
Admiral Perry (3 eps)
Victor Garber
Admiral Halsey (3 eps)
Jason Alexander
Olix (2 eps)
Patrick Warburton
Lt. Tharl (2 eps)
Graham Hamilton
Kaylon Primary (2 eps)
Carlos Bernard
Capt. Marcos (2 eps)
Nick Chinlund
Capt. Dalak (2 eps)
Will Sasso
Mooska (2 eps)
Michaela McManus
Lt. Janel Tyler/Teleya (2 eps)
Greta Jung
Comm. Officer (2 eps)
Kevin Daniels
Locar (2 eps)
Erica Shaffer
Obstetric Surgeon #1 (2 eps)
Jay Whittaker
Kaylon Tertiary (2 eps)
Jamin Thompson
Alien Officer (2 eps)
Francis Lloyd Corby
Crewman (2 eps)
Kelly Hu
Admiral Ozawa (2 eps)
Robert David Grant
Kaylon Secondary (2 eps)
Lesley Fera
Minister Theece (1 eps)
Michael C. Mahon
Altox (1 eps)
Darren Dupree Washington
Simulated Moclan (1 eps)
Jude Lanston
Moclan Prison Guard (1 eps)
Candice King
Solana Kitan (1 eps)
John Billingsley
Cambis Borrin (1 eps)
Kerry O'Malley
Floratta (1 eps)
Mackenzie Astin
Orrin Channing (1 eps)
Aily Kei
Leyna Channing (1 eps)
Giovanni Bejarano
Security Officer (1 eps)
Michael Traynor
Krill Captain (1 eps)
Michele Boyd
Lieutenant Dorsett (1 eps)
Nathan Dana Aldrich
Krill Officer (1 eps)
Arriane Alexander
Regorian Doctor #2 (1 eps)
Brandon Young
Obstetric Surgeon #2 (1 eps)
Cory Tucker
Camp Guard #2 (1 eps)
John Rubinstein
Prefect (1 eps)
Niko Nicotera
Rokal (1 eps)
Jennifer Landon
Ukania (1 eps)
Robert Curtis Brown
Chief Advisor Makkal (1 eps)
Tim Russ
Dr. Sherman (1 eps)
Darri Ingolfsson
Greg (1 eps)
Sarah Scott
Trisha (1 eps)
F. Murray Abraham
Chairman (1 eps)
Ron Canada
Admiral Tucker (1 eps)
Tony Todd
Moclan Delegate (1 eps)
Chase Kim
Officer (1 eps)
Chris Marroy
Rebel (1 eps)
Marina Sirtis
Teacher (1 eps)
Fred Tatasciore
Krill Voice (voice) (1 eps)
Robert Picardo
Ildis Kitan (1 eps)
Molly Hagan
Drenala Kitan (1 eps)
Jake Brennan
James (1 eps)
Adam J. Smith
Nathan (1 eps)
Kristen O'Meara
Jody Duncan (1 eps)
Luke Clark
Kid #1 (1 eps)
Alicia Leigh Willis
Woman (1 eps)
Francesca Catalano
Xelayan Woman (1 eps)
Melvin Diggs
Shuttle Bay Lieutenant (1 eps)
Nicole C. Barnes
Lt. Gomez (1 eps)
Veronica Matheu
Nyxian Girl (1 eps)
Gavin K. Lee
Henry Park (1 eps)
Joseph H. Johnson Jr.
Moclan Doctor (1 eps)
Michael James Lazar
Moclan #1 (1 eps)
Torrance Jordan
Moclan #2 (1 eps)
Aaron McPherson
Crew Member (1 eps)
Chris Flanders
Serris (1 eps)
Heather Horton
Science Prefect (1 eps)
Marie-Françoise Theodore
Advisor #2 (1 eps)
GiGi Hessamian
Physicist (1 eps)
Meredith Thomas
Nurse (1 eps)
Chet Grissom
Aide (1 eps)
Julienne Irons
Prisoner (1 eps)
Charles Maceo
Camp Guard #1 (1 eps)
Chad T. Wood
Warden (1 eps)
Thai Edwards
Holding Cell Guard (1 eps)
Troy Vincent
Man in Lab Coat (1 eps)
April Betts
Engineering Officer (1 eps)
Mark Graham
Conductor (1 eps)
Aaron Goddard
Waiter (1 eps)
Brent Alan Henry
Bartender (1 eps)
Chase Brosamle
Newsie (1 eps)
Vivienne Rutherford
Little Girl (1 eps)
Yvette Tucker
Window Dancer #1 (1 eps)
Steve Hanneman
Window Dancer #2 (1 eps)
Travis Grenke
Space Cadet (1 eps)
Bruce Willis
Groogen (voice) (1 eps)
Chris Bartlett
Kaylon (1 eps)
Stephen Blackehart
Krill Second Officer (1 eps)
Mark Mammone
Crewman (1 eps)
Alveraz Ricardez
Adjutant (1 eps)
Jon Root
Krill Pilot (1 eps)
Paul Rogan
Kaylon Guard #1 (1 eps)
Robin Atkin Downes
Krill Captain Jackazh (1 eps)
John Fleck
Ambassador K.T.Z. (1 eps)
J. Paul Boehmer
Krill High Priest (1 eps)
Max Mittelman
VO from Comm (voice) (1 eps)
Ajay Vidure
Karl (1 eps)
Stacy Highsmith
Melissa (1 eps)
Chris Muto
Richard (1 eps)
Regi Davis
Korick (1 eps)
Shawn Andrew
Toren (1 eps)
Emerson Brooks
Moclan (1 eps)
Cameron Knight
Captain Jakohn (1 eps)
Madelyn Grace
Olivia (1 eps)
Bo Kane
Alien Delegate (1 eps)
Kathrin Middleton
Retepsian Delegate (1 eps)
Mark McClain Wilson
Xelayan Delegate (1 eps)
Hanani Taylor
Moclan Girl (1 eps)
Marlon Sanders
Moclan Soldier #1 (1 eps)
Jerrell Pippens
Moclan Soldier #2 (1 eps)
Sharon Desiree
Yellow Dancing Alien (1 eps)
Randy Jay Burrell
Rebel (1 eps)
Leighton Meester
Laura Huggins (1 eps)
Rena Owen
Heveena (1 eps)
Jim Mahoney
Brosk (1 eps)
Wren T. Brown
Captain Rechik (1 eps)
Yvonne Senat Jones
Osaia (1 eps)
Jack Kennedy
Military Security Guard (1 eps)