Seth MacFarlane
Capt. Ed Mercer (36 eps)
Adrianne Palicki
Cmdr. Kelly Grayson (36 eps)
Penny Johnson Jerald
Dr. Claire Finn (36 eps)
Scott Grimes
Lt. Gordon Malloy (36 eps)
Peter Macon
Lt. Cmdr. Bortus (36 eps)
J. Lee
John LaMarr (36 eps)
Mark Jackson
Isaac (36 eps)
Chad L. Coleman
Klyden (27 eps)
Jessica Szohr
Talla Keyali (24 eps)
Norm Macdonald
Yaphit (voice) (19 eps)
Halston Sage
Alara Kitan (17 eps)
BJ Tanner
Marcus Finn (13 eps)
Kai Wener
Ty Finn (13 eps)
Victor Garber
Admiral Halsey (13 eps)
Anne Winters
Charly Burke (10 eps)
Kyra Santoro
Lieutenant Turco (10 eps)
Kelly Hu
Admiral Ozawa (8 eps)
Larry Joe Campbell
Steve Newton (7 eps)
Rachael MacFarlane
Computer (voice) (7 eps)
Blesson Yates
Topa (7 eps)
Ted Danson
Admiral Perry (6 eps)
Graham Hamilton
Kaylon (5 eps)
Jim Mahoney
Brosk (5 eps)
Rena Owen
Heveena (4 eps)
Michael J. Sielaff
Palovis (4 eps)
Imani Pullum
Topa (4 eps)
Gavin K. Lee
Henry Park (3 eps)
John Fleck
Krill Ambassador (3 eps)
Regi Davis
Dr. Kalba (3 eps)
Andy Milder
Ensign Bolobar (3 eps)
Sarah Jane MacKay
Nurse Hopkins (3 eps)
Bruce Boxleitner
President Alcuzan (3 eps)
Robert David Grant
Kaylon Secondary (3 eps)
Lisa Banes
Speria Balask (3 eps)
Jason Alexander
Olix (2 eps)
Ron Canada
Admiral Tucker (2 eps)
Patrick Warburton
Lt. Tharl (2 eps)
Carlos Bernard
Capt. Marcos (2 eps)
Nick Chinlund
Capt. Dalak (2 eps)
Will Sasso
Mooska (2 eps)
Rob Lowe
Darulio (2 eps)
Michaela McManus
Lt. Janel Tyler/Teleya (2 eps)
Greta Jung
Comm Officer (2 eps)
Fred Tatasciore
Krill Voice (voice) (2 eps)
J. Paul Boehmer
Krill High Priest (2 eps)
Brandon Melendy
Krill Guard (2 eps)
Robert Picardo
Ildis Kitan (2 eps)
Molly Hagan
Drenala Kitan (2 eps)
Jude Lanston
Moclan Prison Guard (2 eps)
Kevin Daniels
Locar (2 eps)
Erica Shaffer
Obstetric Surgeon #1 (2 eps)
Jay Whittaker
Kaylon Tertiary (2 eps)
Jamin Thompson
Alien Officer (2 eps)
Francis Lloyd Corby
Crewman (2 eps)
Randy Jay Burrell
Arachnid Alien (2 eps)
Antonio D. Charity
Advocate Kagus (2 eps)
Jonathan Adams
Moclan Arbitrator (2 eps)
Jeffrey Muller
Lieutenant Ha'Bahl (2 eps)
Leighton Meester
Laura Huggins (2 eps)
Wren T. Brown
Captain Rechik (2 eps)
Yvonne Senat Jones
Osaia (2 eps)
Giorgia Whigham
Lysella (2 eps)
Patrick Cox
Ogre (1 eps)
Brian George
Dr. Aronov (1 eps)
Christine Corpuz
Janice Lee (1 eps)
Sean Cook
Derek (1 eps)
Joel Swetow
Krill Captain (1 eps)
Jeffrey Tambor
Ben Mercer (1 eps)
Holland Taylor
Jeannie Mercer (1 eps)
Mike Gray
Ensign Parker (1 eps)
Glenn Morshower
Admiral Tucker (1 eps)
JD Cullum
Calivon Zoo Administrator (1 eps)
Lamont Thomspon
Kaybrak (1 eps)
Deobia Oparei
Captain Vorak (1 eps)
D. Elliot Woods
Moclan Council Foreman (1 eps)
Robert Knepper
Hamelac (1 eps)
Max Burkholder
Tomilin (1 eps)
Charlize Theron
Pria Lavesque (1 eps)
Dylan Kenin
Captain Haros (1 eps)
James Horan
High Priest Sazeron (1 eps)
Steven Culp
Willks (1 eps)
Barry Livingston
Tom (1 eps)
Loren Lester
Lewis (1 eps)
Brian Thompson
Drogen (1 eps)
Ralph Garman
Kanoot (1 eps)
Lenny Von Dohlen
Valondis (1 eps)
Erica Tazel
Baleth (1 eps)
Philip Anthony-Rodriguez
Fadolin (1 eps)
Jasper McPherson
Little Girl (1 eps)
Jay Jackson
Reporter (1 eps)
Paul Vogt
Horbalak Captain (1 eps)
Gordy De St. Jeor
Teenage Boy (1 eps)
Lesley Fera
Minister Theece (1 eps)
Michael C. Mahon
Altox (1 eps)
Darren Dupree Washington
Simulated Moclan (1 eps)
Candice King
Solana Kitan (1 eps)
John Billingsley
Cambis Borrin (1 eps)
Kerry O'Malley
Floratta (1 eps)
Mackenzie Astin
Orrin Channing (1 eps)
Aily Kei
Leyna Channing (1 eps)
Gabriella Graves
Krill Girl Student (1 eps)
Liam Neeson
Jahavus Dorahl (1 eps)
Giovanni Bejarano
Security Officer (1 eps)
Michael Traynor
Krill Captain (1 eps)
Michele Boyd
Lieutenant Dorsett (1 eps)
Nathan Dana Aldrich
Krill Officer (1 eps)
Arriane Alexander
Regorian Doctor #2 (1 eps)
Brandon Young
Obstetric Surgeon #2 (1 eps)
Cory Tucker
Camp Guard #2 (1 eps)
John Rubinstein
Prefect (1 eps)
Niko Nicotera
Rokal (1 eps)
Jennifer Landon
Ukania (1 eps)
Robert Curtis Brown
Chief Advisor Makkal (1 eps)
Tim Russ
Dr. Sherman (1 eps)
Darri Ingolfsson
Greg (1 eps)
Sarah Scott
Trisha (1 eps)
F. Murray Abraham
Chairman (1 eps)
Tony Todd
Moclan Delegate (1 eps)
Chase Kim
Officer (1 eps)
Chris Marroy
Rebel (1 eps)
Tory Belleci
Calivon Alien (uncredited) (1 eps)
Ethan Jones
Dalen (1 eps)
Marina Sirtis
Teacher (1 eps)
Caleb Brown
Krill Boy Student (1 eps)
Alexis Knapp
Irillia (1 eps)
Amanda Joy Erickson
Amanda (1 eps)
Deep Rai
Crewman (1 eps)
Jonny Siew
Engineer #1 (1 eps)
David Barrera
Vásquez (1 eps)
Rico E. Anderson
Moclan Doctor (1 eps)
Julius Sharpe
Reptilian Alien (1 eps)
Brett Rickaby
Lurenek (1 eps)
Jerry O'Donnell
Captain of the USS Bleriot (1 eps)
Andrew Bering
Technician Jennings (1 eps)
Alaina Fleming
Technician Reed (1 eps)
Jeremy Guskin
Furry Alien (1 eps)
Maxwell Hurlburt
Greenish Alien (1 eps)
Kane Lieu
Security Station Officer (1 eps)
Casey Sander
Druyan Captain (1 eps)
David Hutchison
Alien Man (1 eps)
Michael Dempsey
Mining Chief Harry Leidecker (1 eps)
Makabe Ganey
Coja (1 eps)
Tim Neff
Krill Soldier (1 eps)
Jordan Lane Shappell
Krill Bridge Helmsman (1 eps)
Catherine Shu
Hoshel (1 eps)
John Viener
Talk Show Moderator (1 eps)
Roy Abramsohn
Morning Host (1 eps)
Mike Estes
Guard #1 (1 eps)
Michael Shen
Man in Suit (1 eps)
Brett Easton
Feral Alien Man (1 eps)
Heidi Pascoe
Feral Alien Woman (1 eps)
Tim Soergel
Feral Alien (1 eps)
Derek Mears
Bruidian Ambassador (1 eps)
Stevens Gaston
Ensign Brooks (1 eps)
Alexander Bedria
Voice from Comm (voice) (1 eps)
Nico Birnbaum
Kanoot (voice) (1 eps)
Tim Mikulecky
Lt. Harrison Payne (1 eps)
Seth Allyn Austin
Clown (1 eps)
Leslie Awender
Human Hallway Officer (1 eps)
Roger Berard
Dreamweaver the Mindspider (1 eps)
Sabina Nogic
Human Science Officer (1 eps)
Dan J. Evans
Engineer #1 (1 eps)
Erica Mathlin
Engineer #2 (1 eps)
Preston Bradley
Kaylon Robot (1 eps)
Nick Toren
Man in Red Robe (1 eps)
Neil Dickson
Man in Clerical Garb (1 eps)
Jake Brennan
James (1 eps)
Adam J. Smith
Nathan (1 eps)
Kristen O'Meara
Jody Duncan (1 eps)
Luke Clark
Kid #1 (1 eps)
Alicia Leigh Willis
Woman (1 eps)
Francesca Catalano
Xelayan Woman (1 eps)
Melvin Diggs
Shuttle Bay Lieutenant (1 eps)
Nicole C. Barnes
Lt. Gomez (1 eps)
Veronica Matheu
Nyxian Girl (1 eps)
Joseph H. Johnson Jr.
Moclan Doctor (1 eps)
Michael James Lazar
Moclan #1 (1 eps)
Torrance Jordan
Moclan #2 (1 eps)
Aaron McPherson
Crew Member (1 eps)
Chris Flanders
Serris (1 eps)
Heather Horton
Science Prefect (1 eps)
Marie-Françoise Theodore
Advisor #2 (1 eps)
GiGi Hessamian
Physicist (1 eps)
Meredith Thomas
Nurse (1 eps)
Chet Grissom
Aide (1 eps)
Julienne Irons
Prisoner (1 eps)
Charles Maceo
Camp Guard #1 (1 eps)
Chad T. Wood
Warden (1 eps)
Thai Edwards
Holding Cell Guard (1 eps)
Troy Vincent
Man in Lab Coat (1 eps)
April Betts
Engineering Officer (1 eps)
Mark Graham
Conductor (1 eps)
Aaron Goddard
Waiter (1 eps)
Brent Alan Henry
Bartender (1 eps)
Chase Brosamle
Newsie (1 eps)
Vivienne Rutherford
Little Girl (1 eps)
Yvette Tucker
Window Dancer #1 (1 eps)
Steve Hanneman
Window Dancer #2 (1 eps)
Travis Grenke
Space Cadet (1 eps)
Bruce Willis
Groogen (voice) (1 eps)
Chris Bartlett
Kaylon (1 eps)
Stephen Blackehart
Krill Second Officer (1 eps)
Mark Mammone
Crewman (1 eps)
Alveraz Ricardez
Adjutant (1 eps)
Jon Root
Krill Pilot (1 eps)
Paul Rogan
Kaylon Guard #1 (1 eps)
Robin Atkin Downes
Krill Captain Jackazh (1 eps)
Max Mittelman
VO from Comm (voice) (1 eps)
Ajay Vidure
Karl (1 eps)
Stacy Highsmith
Melissa (1 eps)
Chris Muto
Richard (1 eps)
Shawn Andrew
Toren (1 eps)
Emerson Brooks
Moclan (1 eps)
Cameron Knight
Captain Jakohn (1 eps)
Madelyn Grace
Olivia (1 eps)
Bo Kane
Alien Delegate (1 eps)
Kathrin Middleton
Retepsian Delegate (1 eps)
Mark McClain Wilson
Xelayan Delegate (1 eps)
Hanani Taylor
Moclan Girl (1 eps)
Marlon Sanders
Moclan Soldier #1 (1 eps)
Jerrell Pippens
Moclan Soldier #2 (1 eps)
Sharon Desiree
Yellow Dancing Alien (1 eps)
James Read
Admiral Christie (1 eps)
Elizabeth Gillies
Dinal (1 eps)
Gina Comparetto
Flight Attendant (1 eps)
Farelle Walker
Lieutenant (1 eps)
Eric Satterberg
Teacher (1 eps)
Morgan Bastin
Girl (1 eps)
Ray Benson
Boy (1 eps)
Kendyl Powell
Female Student #1 (1 eps)
Sam Lant
Male Student #1 (1 eps)
Braxton Beckham
Male Student #2 (1 eps)
Jessica Belkin
Popular Girl (1 eps)
Dmitri Schuyler-Linch
Student (1 eps)
Shawn Patrick Clifford
Bully #1 (1 eps)
Richie Rosales
Bully #2 (1 eps)
Chad Guerrero Jr.
Bully #3 (1 eps)
Charlie Townsend
Anaya (1 eps)
Robyn Buck
Krill Woman #2 (1 eps)
Mike Falkow
Krill Dignitary (1 eps)
Senyo Amoaku
Moclan Tactical Officer (1 eps)
Brian Maillard
Lt. Biggins (1 eps)
Jack McBrayer
Actor #1 (1 eps)
Johnny Knoxville
Actor #2 (1 eps)
Michael Andrew Baker
Worker (1 eps)
Ida Anderson
Worker #2 (1 eps)
Jackson Hall
Edward (1 eps)
Tim Mahoney
Brosk (1 eps)
Eliza Taylor
Doctor Villka (1 eps)
Sophina Brown
Captain Losha (1 eps)
Christopher Larkin
Timmis (1 eps)
William R. Moses
Yan (1 eps)
Scott Speiser
Verell (1 eps)
Elyse Levesque
Wenda (1 eps)
Paige Herschell
First Lt. Hodell (1 eps)
Aidan McGraw
Avim (1 eps)
Staci Lawrence
Junior Executive (1 eps)
Stephanie Drapeau
First Officer Kava (1 eps)
Brooke Burgstahler
Ensign Woman (1 eps)
Dolly Parton
Self (1 eps)
Andi Chapman
Admiral Howland (1 eps)
Mark Berry
Commander Kodon (1 eps)
Dirk Rogers
Tongue Alien (1 eps)
Lauren Shaw
Union Guard (1 eps)
Eric C. Sun
Pilot (1 eps)
James Morrison
Kemka (1 eps)
River Drosche
Krill Boy (1 eps)
Armen Nahapetian
Calivon Child (1 eps)
Jack Kennedy
Military Security Guard (1 eps)
Daniel Kash
Krill Commander (1 eps)
Penny Peyser
Customer (1 eps)