George O'Hanlon
George Jetson (voice) (10 eps)
Penny Singleton
Jane Jetson (voice) (10 eps)
Daws Butler
Elroy Jetson (voice) (10 eps)
Janet Waldo
Judy Jetson (voice) (10 eps)
Jean Vander Pyl
Rosie (voice) (10 eps)
Don Messick
Astro (voice) (10 eps)
Mel Blanc
Cosmo S. Spacely (voice) (10 eps)
Frank Welker
Orbitty (voice) (10 eps)
Howard Morris
Harlan (voice) (3 eps)
Brenda Vaccaro
Di-Di (voice) (2 eps)
Allan Melvin
Mr. Spendwell / Construction Worker (voice) (1 eps)
John Stephenson
Commissioner / DWMR Officer (voice) (1 eps)
Lorenzo Music
Florist (voice) (1 eps)
Brian Cummings
Marcia's Father / DJ (voice) (1 eps)
Dan Gilvezan
Randy (voice) (1 eps)
Wink Martindale
Wink Martiandale (voice) (1 eps)