George O'Hanlon
George Jetson (voice) (41 eps)
Penny Singleton
Jane Jetson (voice) (41 eps)
Daws Butler
Elroy Jetson (voice) (41 eps)
Janet Waldo
Judy Jetson (voice) (41 eps)
Jean Vander Pyl
Rosie (voice) (41 eps)
Don Messick
Astro (voice) (41 eps)
Mel Blanc
Cosmo S. Spacely (voice) (41 eps)
Frank Welker
Orbitty (voice) (41 eps)
Howard Morris
Montague Jetson (voice) (4 eps)
Allan Melvin
Mangler Mars (voice) (3 eps)
Barry Gordon
Mechanic (voice) (3 eps)
John Stephenson
Dr. Scarem (voice) (2 eps)
Selma Diamond
Di-Di (voice) (2 eps)
Frank Nelson
Ralph (voice) (2 eps)
Sonny Melendrez
Gus Guesser - Game Show Host (voice) (2 eps)
Foster Brooks
(voice) (1 eps)
Paul Winchell
Dr. Input (voice) (1 eps)
B.J. Ward
Robot / Wicked Wrench of the West (voice) (1 eps)
Didi Conn
Cousin Melissa (voice) (1 eps)
Dave Coulier
Robot Umpire (voice) (1 eps)
René Auberjonois
(voice) (1 eps)
Phil Hartman
School Patrol Robots / Executive Vice President (voice) (1 eps)
Nancy Cartwright
Asteroid Cogswell (voice) (1 eps)
William Windom
Saturn Cyclops (voice) (1 eps)
Rob Paulsen
Jacque Nova / Hall Monitor (voice) (1 eps)
Peter Cullen
Jupiter Juggernaut (voice) (1 eps)
June Foray
Gas Station Woman / Clerk (voice) (1 eps)
Gregg Berger
Curly Quasar (voice) (1 eps)
Lauri Johnson
Mrs. Meltdown (voice) (1 eps)
William Woodson
Narrator (voice) (1 eps)
Roger DeWitt
Sam Spacely (voice) (1 eps)