Alan Reed
Fred Flintstone (voice) (28 eps)
Jean Vander Pyl
Wilma Flintstone (voice) (28 eps)
Bea Benaderet
Betty Rubble (voice) (28 eps)
Mel Blanc
Barney Rubble (voice) (28 eps)
John Stephenson
Mr. Slate (voice) (8 eps)