Sandra Dickinson
Granny Jojo (240 eps)
Kerry Shale
Laurence 'Larry' Needlemeyer (240 eps)
Dan Russell
Richard Watterson (240 eps)
Teresa Gallagher
Nicole Watterson (240 eps)
Kyla Rae Kowalewski
Anais Watterson (240 eps)
Jessica McDonald
Carrie Krueger (240 eps)
Stefan Ashton Frank
Mr. Robinson / Tina Rex / Gaylord Robinson (voice) (240 eps)
Kwesi Boakye
Darwin Watterson (voice) (236 eps)
Jacob Hopkins
Gumball Watterson / Chi Chi (80 eps)
Terrell Ransom Jr.
Darwin Watterson (voice) (80 eps)
Logan Grove
Gumball Watterson (76 eps)
Rupert Degas
Laurence "Larry" Needlemeyer (76 eps)
Nicolas Cantu
Gumball Watterson (voice) (45 eps)
David Warner
Dr. Wrecker (voice) (6 eps)
Rich Fulcher
Frankie Watterson (voice) (3 eps)
Derek Jacobi
Narrator (voice) (2 eps)
Baker Terry
Grady / Frank (voice, puppetry) (1 eps)
Becky Sloan
Howdy (voice, puppetry) (1 eps)
Donielle T. Hansley Jr.
Darwin Watterson (voice) (1 eps)
Garrick Hagon
Superintendent Evil (1 eps)
Brian Blessed
Santa Claus (voice) (1 eps)
Philip Hunt
Fillippo Betto-Hunt (1 eps)
Naoko Mori
Yuki Yoshida (voice) (1 eps)
J.G. Quintel
High-Five Ghost (voice) (1 eps)
Peter Browngardt
Uncle Grandpa (voice) (1 eps)