Jared Padalecki
Sam Winchester (22 eps)
Jensen Ackles
Dean Winchester (22 eps)
Jeffrey Dean Morgan
John Winchester (8 eps)
Nicki Aycox
Meg Masters (4 eps)
Shawn Reis
Tall Deputy (2 eps)
Roy Campsall
Examination Room Spirit (2 eps)
Samantha Smith
Mary Winchester (2 eps)
Jodelle Ferland
Melanie Merchant (1 eps)
Shane Meier
Craig Thursten (1 eps)
Taylor Cole
Sarah Blake (1 eps)
Kyle Labine
Teenage Boy #3 (1 eps)
Erin Karpluk
Monica Holt (1 eps)
Mary Black
Elderly Patient (1 eps)
Alex Ferris
Young Sam Winchester (1 eps)
Agam Darshi
Jill (1 eps)
David Lovgren
Charlie Holt (1 eps)
Nimet Kanji
Passerby (1 eps)
Terence Kelly
Daniel Elkins (1 eps)
Venus Terzo
Joanna (1 eps)
Jay Brazeau
Librarian (1 eps)
Linden Banks
Isaiah Merchant (1 eps)
Lorena Gale
Landlady (1 eps)
Ari Cohen
Miles Tarnower (1 eps)
Britt Irvin
Teenage Girl #1 (1 eps)
Jeannie Epper
La Shtriga (1 eps)
Adrian Hough
Aaron Hydeker (1 eps)
R. D. Call
Sheriff Pierce (1 eps)
Melanie Papalia
Meredith McDonell (1 eps)
A.J. Buckley
Ed Zeddmore (1 eps)
Travis Wester
Harry Spangler (1 eps)
Serinda Swan
Hospital Receptionist (1 eps)
Rondel Reynoldson
Nurse (1 eps)
John Dennis Johnston
Pa Bender (1 eps)
Jessica Steen
Officer Kathleen (1 eps)
Megalyn Echikunwoke
Cassie Robinson (1 eps)
Johnny Cuthbert
Alvin Jenkins (1 eps)
Kathleen Noone
Mrs. Robinson (1 eps)
Brendan Fletcher
Max Miller (1 eps)
Julie Benz
Layla Rourke (1 eps)
Alvin Sanders
Jimmy Anderson (1 eps)
Beth Broderick
Alice Miller (1 eps)
Gary Hetherington
Harold Todd (1 eps)
Rebecca Jenkins
Sue Ann Grange (1 eps)
Kevin McNulty
Roy Le Grange (1 eps)
Tania Saulnier
Emily Jorgeson (1 eps)
Tom Butler
Harley Jorgeson (1 eps)
P. Lynn Johnson
Stacey Jorgeson (1 eps)
William B. Davis
College Professor (1 eps)
Brooke Nevin
Katherine (1 eps)
Nicholas D'Agosto
Gavin (1 eps)
Tom Pickett
Daniel Gunderson (1 eps)
Andrew Airlie
Larry Pike (1 eps)
Carrie Genzel
Lynda Bloome (1 eps)
Kristin Richardson
Jenny (1 eps)
Tyler Johnston
Matt Pike (1 eps)
Marnette Patterson
Charlie (1 eps)
Dan Butler
Reverend Sorenson (1 eps)
Jane McGregor
Lori Sorenson (1 eps)
William S. Taylor
Detective (1 eps)
Chelan Simmons
Jill (1 eps)
Brian Skala
Rich (1 eps)
Amy Grabow
Rebecca Warren (1 eps)
Kristie Marsden
Donna Shoemaker (1 eps)
Alf Humphreys
Sheriff (1 eps)
Jaime Ray Newman
Amanda Walker (1 eps)
Brian Markinson
Jerry Panowski (1 eps)
Callum Keith Rennie
Roy (1 eps)
Daniel Hugh Kelly
Jake Devins (1 eps)
Sarah Shahi
Constance Welch (1 eps)
Ross Kohn
Troy Squire (1 eps)
Steve Railsback
Joseph Welch (1 eps)
Jamil Walker Smith
Luis (1 eps)
Donnelly Rhodes
Mr. Shaw (1 eps)
Cory Monteith
Gary (1 eps)
Paul Jarrett
George Phelps (1 eps)
Geoff Gustafson
Lou (1 eps)
Genevieve Buechner
Lily Shoemaker (1 eps)
Peter Shinkoda
Alex (1 eps)
Chelah Horsdal
Cute Librarian (1 eps)
Sean Millington
Hook Man (1 eps)
Christie Laing
Taylor (1 eps)
Ryan Robbins
Travis Weaver (1 eps)
Jim Byrnes
Professor (1 eps)
Anne Marie DeLuise
Joanie Pike (1 eps)
Michael Daingerfield
Dustin Burwash (1 eps)
Peter Benson
Walter Kelly (1 eps)
Brendan Penny
Steve (1 eps)
Colin Lawrence
Jason (1 eps)
Alex Diakun
Reaper (1 eps)
Alexia Fast
Missy Bender (1 eps)
Ken Kirzinger
Jared Bender (1 eps)
Erica Carroll
Young Mother (1 eps)
Josh Blacker
Caleb (1 eps)
Krista Bell
Dana (1 eps)
Keith Martin Gordey
Daniel Blake (1 eps)
Curtis Caravaggio
Mark Telesca (1 eps)
Joshua D. Clark
Mover (1 eps)
Damon Runyan
Jenny's Boyfriend (1 eps)
Sarah Mutch
Brandi (1 eps)
Brenda Campbell
Beth (1 eps)
Dominic Zamprogna
Beau (1 eps)
Warren Christie
Luther (1 eps)
Sean Tyson
Trucker (1 eps)
Matt Riley
Firefighter (1 eps)
Ridge Canipe
Young Dean Winchester (1 eps)
Richard Sali
Jim Murphy (1 eps)
Anne Openshaw
Kate (1 eps)
Kenton Reid
Waiter (1 eps)
Colby Paul
Michael (1 eps)
Barbara Frosch
Evelyn (1 eps)
Stacee Copeland
Betty (1 eps)
John Prowse
Motel Owner (1 eps)
Chandra Berg
Gloria (1 eps)
Colby Johannson
James (1 eps)
Jason Griffith
Sheriff (1 eps)
Jay-Nicolas Hackleman
Teenage Boy #2 (1 eps)
Natasha Peck
Teenage Girl #2 (1 eps)
Gerry Mackay
Mr. Goodwin (1 eps)
Nicholas Harrison
Mordechai Murdoch (1 eps)
Ryan Drescher
Evan McKay (1 eps)
Sandra Steier
Dispatcher (voice) (1 eps)
Sadie Lawrence
Mrs. McKay (1 eps)
Fred Keating
Neighbor Man (1 eps)
Avery Raskin
Roger Miller (1 eps)
Susinn McFarlen
Neighbor Lady (1 eps)
Dalias Blake
Policeman (1 eps)
Cameron McDonald
Jim Miller (1 eps)
Dee Jay Jackson
Dockworker (1 eps)
Michael Busswood
Ron Stubbins (1 eps)
Gillian Barber
Mrs. Rourke (1 eps)
Ron Robinson
Young Martin Robinson (1 eps)
Jim Codrington
Male Doctor (1 eps)
Woody Jeffreys
Marshall Hall (1 eps)
Tiffany Lyndall-Knight
Female Doctor (1 eps)
Aaron Craven
David Wright (1 eps)
Scott E. Miller
Cop #1 (1 eps)
Pat Waldron
Cop #2 (1 eps)
Brent Stait
Scotty (1 eps)
David Orth
Sheriff (1 eps)
Dean Wray
Driver #1 (1 eps)
Christian Schrapff
Vince Parker (1 eps)
Leah Graham
Pauly (1 eps)
Angela Moore
Bus Station Clerk (1 eps)
James Purcell
James Ellicott (1 eps)
Norman Armour
Sanford Ellicott (1 eps)
Karly Warkentin
Mrs. Kelly (1 eps)
Nicole LaPlaca
Kissing Spirit (1 eps)
Richard Dietl
Bar Patron (1 eps)
Leif Bridgman
Straight Jacket Spirit (1 eps)
Don Thompson
Mr. Guenther (1 eps)
Jerry Rector
Joe (1 eps)
Ginger Page
Sari (1 eps)
Jamie Schwanebeck
Richie (1 eps)
Jimmy Herman
Joe Whitetree (1 eps)
Mi-Jung Lee
Anchorwoman (1 eps)
Mike Waterman
Murph (1 eps)
Benjamin Rogers
Mark (1 eps)
Marrett Green
Anchorman (1 eps)
Anita Brown
Lindsay (1 eps)
Shiraine Haas
Bystander (1 eps)
Aleks Holtz
Zach Warren (1 eps)
Michael Teigen
Teacher (1 eps)
James Ashcroft
Coroner (1 eps)
Duncan Minett
Steven Shoemaker (1 eps)
Jessica King
Lily's Friend #1 (1 eps)
Victoria Tennant
Lily's Friend #2 (1 eps)
Jovanna Huguet
Mary Worthington (1 eps)
Birkett Turton
Max Jaffe (1 eps)
Daryl Shuttleworth
Chuck Lambert (1 eps)
Fred Henderson
Homeland Security Man #2 (1 eps)
Amanda Wood
Flight Attendant (1 eps)
Ingrid Tesch
Bonnie Phelps (1 eps)
Kelly-Ruth Mercier
Woman Passenger (1 eps)
Dana Pemberton
Security Guard (1 eps)
Benjamin Ayres
Homeland Security Man #1 (1 eps)
Bruce Dawson
Bill Carlton (1 eps)
Bethoe Shirkoff
Mrs. Sweeney (1 eps)
Nico McEown
Lucas Barr (1 eps)
D. Harlan Cutshall
Fisherman (1 eps)
Troy Clare
Will Carlton (1 eps)
Amber Borycki
Sophie Carlton (1 eps)
Keira Kabatow
Waitress (1 eps)
Timothy Webber
Ranger Wilkinson (1 eps)
Wren Roberts
Brad (1 eps)
Tamara Lashley
Paramedic (1 eps)
Rhys Williams
Local (1 eps)
Derek Webster
Deputy Jaffe (1 eps)
Elizabeth Bond
Amy Hein (1 eps)
Miriam Korn
Rachel (1 eps)
Cletus Young
Motel Clerk (1 eps)
Robert Peters
Deputy Hein (1 eps)
Nancy Bell
Old woman spirit (1 eps)
Alden Ehrenreich
Ben Collins (1 eps)
Amy Acker
Andrea Barr (1 eps)
Gina Holden
Haley Collins (1 eps)
Graham Wardle
Tommy Collins (1 eps)
Aaron Rota
Peter Sweeney (1 eps)
Jim Beaver
Bobby Singer (1 eps)
Jody Thompson
Ann Telesca (1 eps)
Hunter Brochu
Young Dean (1 eps)
Christine Chatelain
Jenny (1 eps)