Amy Sedaris
Jerri Blank (10 eps)
Paul Dinello
Geoffrey Jellineck (10 eps)
Stephen Colbert
Chuck Noblet (10 eps)
Greg Hollimon
Onyx Blackman (10 eps)
Patrick Blindauer
Chip Beavers (3 eps)
Kelly Hutchinson
Sylvia (3 eps)
Troy Metcalf
Troy (3 eps)
Justin Daniel
Casper (2 eps)
Andy Richter
Tweetzie Railroad Indian (2 eps)
David Pasquesi
Stew (2 eps)
Virginia Williams
Wilma (2 eps)
Will Ferrell
Bob Whitely (1 eps)
Winona Ryder
Fran (1 eps)
Jack Ferver
Jimmy Tickles (1 eps)
Bernie McInerney
Dr. Zorters (1 eps)
Derek Richardson
Jared (1 eps)
Sanjiv Jhaveri
Cab Driver (1 eps)
Joseph Culliton
V.D. Doctor (1 eps)
Dylan Baker
Minister Arsenew (1 eps)
Peter Hans Benson
Buddah Stalin (1 eps)
Ryan Patrick Bachand
Arnie Arsenew (1 eps)
Michael Cruz
Wendell (1 eps)
Kimberley Masters
Student (1 eps)
Jackie Tohn
Heckler (1 eps)
Chris Carmack
Laird (1 eps)
Heather Matarazzo
Renee (1 eps)
David Cross
Dr. Trepanning (1 eps)
Valentine Bureau
Trudy (1 eps)
Matthew Sean Blumm
P-John (1 eps)
Jay Martel
Captain Stacks (1 eps)
Tim Miller
Mr. Kolovitz (1 eps)
Erin Cottrell
Relay Team Member (1 eps)
Carla Greene
Jackie (1 eps)
James Saito
Drug Tester (1 eps)
Sophina Brown
Sydney (1 eps)
Eunice Wong
Ghost Girl (1 eps)
Joshua Harto
Stoner Kid (1 eps)
Marcel Simoneau
Troubled Youth (1 eps)
Larry Marshall
Jazzy (1 eps)
Jamie Bennett
Skeet (1 eps)
Judson Pearce Morgan
Miles (1 eps)
Sue Gisser
Stravulla (1 eps)
Gregory Barkhamer
Student (1 eps)
Ross Bickell
Mr. Tidbits (1 eps)
Natalie Blalock
Edie Harley (1 eps)
Callie Thorne
School Nurse (1 eps)
Janeane Garofalo
Cassie Pines (1 eps)
Mark McKinney
Lee (1 eps)
Cheri Oteri
Hillary (1 eps)
Paul Rudd
Brent Brooks (1 eps)
Ming Lee
Dry Cleanery Employee (1 eps)