Richard Chamberlain
Pilot-Major John Blackthorne / Anjin-san (5 eps)
Toshirō Mifune
Lord Yoshi Toranaga (5 eps)
Yoko Shimada
Lady Toda Buntaro - Mariko (5 eps)
John Rhys-Davies
Vasco Rodrigues (5 eps)
Alan Badel
Father Dell'Aqua (5 eps)
Frankie Sakai
Yabu (5 eps)
Vladek Sheybal
Captain Ferriera (5 eps)
Yûki Meguro
Omi (5 eps)
Michael Hordern
Friar Domingo (5 eps)
George Innes
Johann Vinck (5 eps)
Damien Thomas
Father Alvito (5 eps)
Hideo Takamatsu
Lord Buntarō (5 eps)
Hiromi Senno
Fujiko (5 eps)
Leon Lissek
Father Sebastio (5 eps)
Nobuo Kaneko
Ishido (5 eps)
Takeshi Ōbayashi
Urano (5 eps)
Hiroshi Hasegawa
Galley Captain (5 eps)
Akira Sera
Old Gardener (5 eps)
Atsuko Sano
Lady Ochiba (5 eps)
Miiko Taka
Kiri (5 eps)
Masumi Okada
Brother Michael (5 eps)
Edward Peel
Pieterzoon (5 eps)
Eric Richard
Maetsukker (5 eps)
Neil McCarthy
Spillbergen (5 eps)
Seiji Miyaguchi
Muraji (5 eps)
Yōsuke Natsuki
Zataki (5 eps)
William Morgan Sheppard
Specz (5 eps)
Shin Takuma
Naga (5 eps)
Ai Matsubara
Rako (5 eps)
John J. Carney
Ginsel (5 eps)
Tōru Abe
Hiromatsu (5 eps)
Orson Welles
Narrator (5 eps)
Anne Bancroft
Narrator (5 eps)