Tracy Spiridakos
Charlotte "Charlie" Matheson (22 eps)
Billy Burke
Miles Matheson (22 eps)
David Lyons
Sebastian "Bass" Monroe (22 eps)
Giancarlo Esposito
Major Tom Neville (22 eps)
Zak Orth
Aaron Pittman (22 eps)
J. D. Pardo
Jason Neville (22 eps)
Stephen Collins
Dr. Gene Porter (22 eps)
Elizabeth Mitchell
Rachel Matheson (22 eps)
Steven Culp
Edward Truman (14 eps)
Mat Vairo
Connor Bennett (12 eps)
Maureen Sebastian
Priscilla Pittman (11 eps)
Jessica Collins
Cynthia (10 eps)
Nicole Ari Parker
Secretary Justine Allenford (8 eps)
Christopher Cousins
Victor Doyle (7 eps)
Zeljko Ivanek
Dr. Calvin Horn (5 eps)
Cotter Smith
President Jack Davis (5 eps)
Billy Lush
Scanlon (5 eps)
Matt Ross
Titus Andover (4 eps)
Kim Raver
Julia Neville (4 eps)
Barry Tubb
Malcolm Dove (4 eps)
Waleed Zuaiter
Martin Shaw (4 eps)
David Aaron Baker
Roger Allenford (4 eps)
Reiko Aylesworth
Marion Kelly (4 eps)
Anthony Ruivivar
General Bill Carver (4 eps)
Richard T. Jones
Ken Dawson (3 eps)
Patrick Heusinger
Adam (3 eps)
Daniel Henney
Peter Garner (3 eps)
Adam Beach
Sheriff Mason (2 eps)
Maria Howell
Grace Beaumont (2 eps)
Jim Beaver
John Franklin Fry (2 eps)
Katie Aselton
Duncan Page (2 eps)
Timm Sharp
Gould (2 eps)
M.C. Gainey
Frank Blanchard (2 eps)
Colby French
Joe Matthews (2 eps)
Blake Hood
Jeff (1 eps)
Adam Sinclair
Carl (1 eps)
Alanna Ubach
Bonnie Webster (1 eps)
Aidan Sussman
Boy (1 eps)
Joaquim de Almeida
Luis Nunez (1 eps)
Bret Michaels
Himself (1 eps)
Arthur Marroquin
Ghost (uncredited) (1 eps)
Cody Sullivan
Young Calvin Horn (1 eps)
Tyrees Allen
Grant Carson (1 eps)
Gonzalo Menendez
Leonard Baylor (1 eps)
Kate Boyer
Carl's Girl (1 eps)