Wentworth Miller
Michael Scofield (22 eps)
Marshall Allman
LJ Burrows (22 eps)
Dominic Purcell
Lincoln Burrows (22 eps)
Sarah Wayne Callies
Sara Tancredi (22 eps)
Paul Adelstein
Paul Kellerman (22 eps)
Wade Williams
Brad Bellick (22 eps)
Rockmond Dunbar
Benjamin "C-Note" Franklin (22 eps)
Robert Knepper
Theodore "T-Bag" Bagwell (22 eps)
Amaury Nolasco
Fernando Sucre (22 eps)
Peter Stormare
John Abruzzi (22 eps)
Robin Tunney
Veronica Donovan (22 eps)
Stacy Keach
Warden Henry Pope (22 eps)
Muse Watson
Charles Westmoreland (22 eps)
Danny McCarthy
Danny Hale (18 eps)
Frank Grillo
Nick Savrinn (16 eps)
Phillip Edward Van Lear
Louis Patterson (11 eps)
Christian Stolte
Stolte (7 eps)
Jennifer Joan Taylor
Becky (7 eps)
Michelle Forbes
Samantha Brinker (7 eps)
DuShon Monique Brown
Katie Welch (6 eps)
Mac Brandt
Mack Andrews (6 eps)
Jessalyn Gilsig
Lisa Rix (5 eps)
Matt DeCaro
Roy Geary (4 eps)
Al Sapienza
Philly Falzone (4 eps)
John Heard
Frank Tancredi (4 eps)
Rich Komenich
Maggio (4 eps)
Anthony Fleming
Trumpets (4 eps)
Camille Guaty
Maricruz Delgado (3 eps)
Gianni Russo
Smallhouse (3 eps)
Anthony Starke
Sebastian (3 eps)
Scott Jaeck
Trenchcoat (3 eps)
Chelcie Ross
Bishop McMorrow (2 eps)
Adina Porter
Leticia Barris (2 eps)
Ora Jones
Wendy (2 eps)
Daniel Allar
Avocado (2 eps)
Michael Cudlitz
Robert "Bob" Hudson (2 eps)
Deanna Dunagan
Judy (2 eps)
Linara Washington
Jenae Conlin (2 eps)
Kwame Amoaku
Stroker (2 eps)
Philip Rayburn Smith
Adrian (2 eps)
Jennifer Kern
Allison Hale (2 eps)
Michael Vieau
Trokey (2 eps)
Blaine Hogan
Seth/Cherry (2 eps)
Michael Gaston
Quinn (2 eps)
Wesley Walker
Aryan Brother (2 eps)
Kurt Caceres
Hector (2 eps)
John Billingsley
Terrence Steadman (2 eps)
Keith Diamond
Tim Giles (1 eps)
Tab Baker
Crab Simmons (1 eps)
John Judd
Ben (1 eps)
Cedric Young
Chappy (1 eps)
Jason Wells
Bo (1 eps)
Joe Minoso
Chaz Fink (1 eps)
Malieek Straughter
Wholesale (1 eps)
Michael L. Howard
Inmate (1 eps)
Morocco Omari
Ron (1 eps)
Michael Stoyanov
Fletch (1 eps)
John Turk
Turk (1 eps)
Cynthia Kaye McWilliams
Kacee Franklin (1 eps)
Danielle Campbell
Gracey Hollander (1 eps)
Jacqueline Williams
Sue Parsons (1 eps)
Denise Hughes
Bus Driver (1 eps)
Howie Johnson
Lukasz (1 eps)
Rebecca Spence
Shauna Hudson (1 eps)
David Darlow
Dr. Brighton (1 eps)
Roderick Peeples
Fibonacci (1 eps)
Mary Beth Fisher
Leslie Steadman (1 eps)
Larry Neumann Jr.
Jimmy Bagwell (1 eps)
Tom McElroy
Reverendo Mailor (1 eps)
Robert Breuler
Dr. Wasserman (1 eps)
Joel Hatch
Giudice Kessler (1 eps)
Mike Bacarella
Red Bull (1 eps)
Ellis Foster
Zach (1 eps)
Roddy Chiong
Pao (1 eps)
José Antonio García
Jesus (1 eps)
Will Zahrn
Sceriffo Ballard (1 eps)
Lea Coco
Coco (1 eps)
Kurt Naebig
Ray (1 eps)
Daniel J. Travanti
Richard Mills (1 eps)
Antoine McKay
Antoine (1 eps)
Andrew Rothenberg
Sklar (1 eps)
Sephus Booker
C.O. (1 eps)
Scott Westerman
Maintenance Guy (1 eps)