Tatiana Maslany
Sarah / Cosima / Alison / Helena / Rachel (10 eps)
Dylan Bruce
Paul Dierden (10 eps)
Jordan Gavaris
Felix 'Fee' Dawkins (10 eps)
Maria Doyle Kennedy
Siobhan 'Mrs. S' Sadler (10 eps)
Ari Millen
Mark / Rudy / Miller / Ira (10 eps)
Kevin Hanchard
Detective Arthur 'Art' Bell (10 eps)
Kristian Bruun
Donald 'Donnie' Hendrix (10 eps)
Evelyne Brochu
Delphine Cormier (10 eps)
Kyra Harper
Dr. Virginia Coady (9 eps)
Zoé De Grand Maison
Gracie Johanssen (8 eps)
Tom McCamus
Dr. Alan Nealon (6 eps)
Ksenia Solo
Shay Davydov (6 eps)
Millie Davis
Gemma Hendrix (5 eps)
Amanda Brugel
Marci Coates (5 eps)
Skyler Wexler
Kira Manning (4 eps)
Justin Chatwin
Jason Kellerman (4 eps)
Carlos Gonzalez-Vio
Dr. Silva (4 eps)
Tom Barnett
David Benchman (4 eps)
James Frain
Ferdinand Chevalier (3 eps)
Earl Pastko
Bulldog (3 eps)
Trenna Keating
Vera (3 eps)
Diana Salvatore
Bobby (2 eps)
Terra Hazelton
Sarah Stubbs (2 eps)
Kristin Booth
Bonnie Johanssen (2 eps)
Alison Steadman
Kendall Malone (2 eps)
Rosemary Dunsmore
Professor Susan Duncan (2 eps)
Tony Cianchino
Pouchy (2 eps)
David Vena
Joao (2 eps)
Cynthia Galant
Young Rachel / Charlotte (2 eps)
Allen Keng
Painmaker (2 eps)
Kathryn Alexandre
Alexis (2 eps)
Monica Dottor
Soccer Mom (2 eps)
Natalie Krill
Patty (2 eps)
Gavin Fox
Lionel (2 eps)
Jess Salgueiro
Luisa (2 eps)
Michelle Arvizu
La Camarera (2 eps)
Michiel Huisman
Cal Morrison (1 eps)
Patrick J. Adams
Jesse (1 eps)
Andrew Gillies
Ethan Duncan (1 eps)
Allan Turner
Young Ethan Duncan (1 eps)
Desmond Campbell
Guard One (1 eps)
Chris Gallinger
Guard Two (1 eps)
Nicholas Campbell
Willard Finch (1 eps)
David Fox
Jonah Appleyard (1 eps)
Andrew Priestman
Soldier (1 eps)
Ryan Turner
Soldier Hastings (1 eps)
Sabrina Persaud
EMT (1 eps)
Ryan Allen
Soldier Woods (1 eps)
Sheila McCarthy
Connie Hendrix (1 eps)
Alejandro Ampudia
Hernan (1 eps)
David Bronfman
Bob Buckingham (1 eps)
Mary Kelly
Stacey Horowitz (1 eps)
Lucie Guest
Zoie (1 eps)
Taylor Price
German Doctor (1 eps)
Nigel Bennett
Kassov (1 eps)
Daniel Fathers
Terrance (1 eps)
W. Joseph Matheson
Christy (1 eps)
Keiran Kennedy
Keiran (1 eps)
Brittany Drisdelle
DYAD Receptionist (1 eps)
Kimmy Choi
DYAD Orderly (1 eps)
Azdin Zaman
Meera's Husband / Voting Husband (1 eps)
Alexis Koetting
Voting Wife (1 eps)
Christy Bruce
Young Susan Duncan (1 eps)
Calwyn Shurgold
Hell Wizard (1 eps)