Chad Michael Murray
Lucas Scott (18 eps)
James Lafferty
Nathan Scott (18 eps)
Bethany Joy Lenz
Haley James Scott (18 eps)
Sophia Bush
Brooke Davis (18 eps)
Hilarie Burton
Peyton Sawyer (18 eps)
Jackson Brundage
Jamie Scott (18 eps)
Lee Norris
Marvin 'Mouth' McFadden (18 eps)
Paul Johansson
Dan Scott (18 eps)
Antwon Tanner
Antwon 'Skills' Taylor (18 eps)
Michaela McManus
Lindsey Strauss (15 eps)
Robbie Jones
Quentin Fields (12 eps)
Lisa Goldstein Kirsch
Millicent Huxtable (11 eps)
Torrey DeVitto
Carrie (9 eps)
Daphne Zuniga
Victoria Davis (7 eps)
Kate Voegele
Mia Catalano (7 eps)
Bradley Evans
Jerry (6 eps)
Kelly Collins Lintz
Alice Day (5 eps)
Joe Manganiello
Owen Morello (5 eps)
Vaughn Wilson
Fergie (5 eps)
Cullen Moss
Junk (5 eps)
Barbara Alyn Woods
Deb Scott (4 eps)
Kevin Federline
Jason (3 eps)
Wilbur Fitzgerald
Bill (3 eps)
Chris Beetem
Dr. Copeland (3 eps)
Lee Spencer
News Director (3 eps)
Danneel Ackles
Rachel Gatina (2 eps)
Kieren Hutchison
Andy Hargrove (2 eps)
Dikran Tulaine
John Knight (2 eps)
Hailey Wist
Molly (2 eps)
Mary Kate Englehardt
Lily (2 eps)
David Hains
Rick (2 eps)
Barry Corbin
Whitey Durham (1 eps)
Moira Kelly
Karen Roe (1 eps)
Joseph Gallison
Senior Editor (1 eps)
Johann Urb
Nick (1 eps)
Gavin DeGraw
Gavin DeGraw (1 eps)
Brendan Kirsch
Brendan (1 eps)
Mark Schwahn
Max (1 eps)
William Day
Barry (1 eps)
Karen Ceesay
Receptionist (1 eps)
Shawn Shepard
Principal Turner (1 eps)
Rand Courtney
Greg (1 eps)
Bevin Prince
Bevin (1 eps)
Jason Giuliano
Guy (1 eps)
Brett Claywell
Tim Smith (1 eps)
Justin Tully
Interviewer (1 eps)
Southey Blanton
Fan (1 eps)
Brett Kelley
Bartender (1 eps)
Jonathan Frappier
Executive (1 eps)
Carissa Capobianco
Amy (1 eps)
Aerli Austen
TV Employee (1 eps)
Taylor Kowalski
Flower Guy (1 eps)
Dominic L. Santana
Policeman (1 eps)
Haviland Morris
Olivia Pruitt (1 eps)
Marcus Hester
Vincent (1 eps)
Judith Scott
Adoption Worker (1 eps)
Tony Vaughn
Doctor (1 eps)
Rus Blackwell
Sam (1 eps)
Nancy Young
Nurse (1 eps)
Rick Clark
Rick (1 eps)
Victor Turner
Layout Manager (1 eps)
Reegus Flenory
Guard (1 eps)
Kelly Jones Gabriele
Woman (1 eps)
Bradley Tharington
Alice's Date (1 eps)
Ed Wagenseller
Reporter (1 eps)
Shon Blotzer
Co-Worker (1 eps)
Jayce O'Neal
Waiter (1 eps)
Katie Hayek
Ticket Agent (1 eps)
Tiffany T. Williams
Hostess (1 eps)
Amoreena Wade
Waitress (1 eps)
Jon Stafford
Driver (1 eps)
Kenny Gasperson
Carlton (1 eps)
Alissa Laderer
Drunk Girl (1 eps)
Rick Hamilton
Administrator (1 eps)
Cari Moskow
Patty (1 eps)
Doug Haupt
Minister (1 eps)
Fran Tabor
Violinist (1 eps)
Allie Taylor
Nanny #1 (1 eps)
Quentin Kerr
Manny (1 eps)
Chris McNair
Bucko (1 eps)
Jennifer Massey
Female Executive (1 eps)
Shaun Collins
Player #1 (1 eps)
Gary Marsh
Player #2 (1 eps)
Antonio Todd
Coach Todd (1 eps)
Gil Newsom
Ref (1 eps)
Kevin Ryan
Ronnie (1 eps)
Steffen Schollaert
Cameraman (1 eps)
Kevin Otos
Doctor (1 eps)
Tom Werme
Steve (1 eps)