Chad Michael Murray
Lucas Scott (23 eps)
James Lafferty
Nathan Scott (23 eps)
Bethany Joy Lenz
Haley James Scott (23 eps)
Sophia Bush
Brooke Davis (23 eps)
Hilarie Burton
Peyton Sawyer (23 eps)
Barry Corbin
Whitey Durham (23 eps)
Craig Sheffer
Keith Scott (23 eps)
Moira Kelly
Karen Roe (23 eps)
Paul Johansson
Dan Scott (23 eps)
Barbara Alyn Woods
Deb Scott (23 eps)
Kieren Hutchison
Andy Hargrove (16 eps)
Lee Norris
Marvin 'Mouth' McFadden (15 eps)
Michael Copon
Felix Taggaro (12 eps)
Daniella Alonso
Anna Taggaro (12 eps)
Bryan Greenberg
Jake Jagielski (11 eps)
Maria Menounos
Jules (10 eps)
Tyler Hilton
Chris Keller (9 eps)
Brett Claywell
Tim Smith (7 eps)
Vaughn Wilson
Fergie (7 eps)
William Haze
Rick (7 eps)
Antwon Tanner
Antwon 'Skills' Taylor (5 eps)
Katherine Bailess
Erica Marsh (5 eps)
Bevin Prince
Bevin (5 eps)
Cullen Moss
Junk (5 eps)
Lindsey McKeon
Taylor James (4 eps)
Emmanuelle Vaugier
Nicki (4 eps)
Johnny Alonso
Joey D (3 eps)
Shawn Shepard
Principal Turner (3 eps)
Huey Lewis
Jimmy James (2 eps)
Bess Armstrong
Lydia James (2 eps)
Steven Roten
Waiter (2 eps)
Matthew Laurance
Doctor (2 eps)
Sarah Edwards
Theresa (2 eps)
Linsey Godfrey
Barb (1 eps)
Summer Altice
Simone (1 eps)
Nick Zano
Nick Zano (1 eps)
Stuart Lafferty
Jarrett Green (uncredited) (1 eps)
Austin Carty
Young Dan (1 eps)
Emeka Okafor
Emeka Okafor (1 eps)
Peter Jurasik
Carl (1 eps)
Fred Norris
Wedding Photographer (1 eps)
Henry Darrow
Doctor (1 eps)
Blake Bashoff
Gary Matheson (1 eps)
Schuyler Fisk
Daytona Green (1 eps)
Michael Trucco
Cooper Lee (1 eps)
Chris Potter
Ray Green (1 eps)
Nancy Moreno
Young Karen (1 eps)
Randell Haynes
Science Teacher (1 eps)
E. Roger Mitchell
Technician (1 eps)
Elisabeth Lewis Corley
Woman (1 eps)
Sallie Hedrick
Sales Girl (1 eps)
Mark Scarboro
Maitre D' (1 eps)
Chuck Kinlaw
Security Guard (1 eps)
Maria Magno
Masseuse (1 eps)
Andrea Maddox
Sales Girl #2 (1 eps)
Carl McIntyre
Priest (1 eps)
Rob Zapple
Fire Marshall (1 eps)
Timmy Sherrill
Rocker (1 eps)
Avis-Marie Barnes
Marion (1 eps)
Heather Shore
Nurse (1 eps)
R. Keith Harris
Surgeon (1 eps)
Joseph Gallison
Minister (1 eps)
Leesa Castaneda
Nurse #2 (1 eps)
Jeffrey West
Doctor (1 eps)
Brad Carlson
Really Cute Guy (1 eps)
Wayne Adams
Amazingly Cute Guy (1 eps)
Amanda Baker
Charlotte (1 eps)
Tenia Taylor
Tenia (1 eps)
Nicky Buggs
Officer Bernstein (1 eps)
Grace Junot
Officer Grasso (1 eps)
Erich Campbell
Mechanic (1 eps)
David Sherrill
Strip Club Owner (1 eps)
Sylvia Jefferies
Instructor (1 eps)
Ashley Novasad
Clerk (1 eps)
Dane Hereford
Bru-Dog (1 eps)
Rodney Lee Rogers
Technician (1 eps)
Calvin Brown
Engineer (1 eps)
Abbey Wade
Marla (1 eps)
Gail Borges
Adela (1 eps)
Anthony Jones
Dewey (1 eps)
Ryan Sweeney
Jock (1 eps)
Michelle Branch
Michelle Branch (1 eps)
Jessica Harp
Jessica Harp (1 eps)
Christopher Corbin
50's Boy (1 eps)
Jayson Frederick
Guy (1 eps)
Steve Coulter
Mediator (1 eps)
Michelynne McGuire
Charlotte (1 eps)
Ken Carrington
Security Guard (1 eps)
Chris Wayne
Stagehand (1 eps)
Sprague Grayden
Darby (1 eps)
Robert Pralgo
Attorney (1 eps)
Bourke Floyd
Police Officer (1 eps)
Jim Coleman
Officer #2 (1 eps)
Stewart J. Zully
Detective (1 eps)
Roberto Escobar
Mr. Taggaro (1 eps)
Nanci Hernandez-Hall
Mrs. Taggaro (1 eps)
Katherine Stuart Mintz
Dancer #1 (1 eps)
Kristen Jeannine Dalton
Dancer #2 (1 eps)
Jane Beck
Dancer #3 (1 eps)
Jeff Burton
Jeff Burton (1 eps)
Rodney Roldan
EMT (1 eps)
Leonard Wheeler
Customer (1 eps)
Déjá Dee
Nurse (1 eps)
Ron Clinton Smith
Otis (1 eps)
Nicole Travolta
Female Roadie (1 eps)
Andrea Powell
Joan (1 eps)
Joe Inscoe
Teacher (1 eps)
Eric Hissom
Guard (1 eps)
Jennifer Peña
Girl #1 (1 eps)
Jacob Haines
Greg (1 eps)
Chelsea Pfeiffer
Singing Girl (1 eps)
Spencer Cain
Guy (1 eps)
Sheryl Lee
Ellie Harp (1 eps)
Brien Gregorie
Driver (1 eps)
Jamie Bozian
Strip Club Manager (uncredited) (1 eps)
Timothy Woodward Jr.
Frat Guy (uncredited) (1 eps)
Noah Michael Levine
Electrician (1 eps)
Jeannette Weegar
Ms. Hand (1 eps)