Bonnie Franklin
Ann Romano (210 eps)
Valerie Bertinelli
Barbara Cooper (210 eps)
Pat Harrington, Jr.
Dwayne Schneider (210 eps)
Mackenzie Phillips
Julie Cooper (168 eps)
Michael Lembeck
Max Horvath (80 eps)
Glenn Scarpelli
Alex Handris (72 eps)
Boyd Gaines
Mark Royer (59 eps)
Nanette Fabray
Katherine Romano (51 eps)
Shelley Fabares
Francine Webster (41 eps)
Richard Masur
David Kane (40 eps)
Howard Hesseman
Sam Royer (30 eps)
Mary Louise Wilson
Ginny Wroblicki (24 eps)
Ron Rifkin
Nick Handris (21 eps)
John Putch
Bob Morton (14 eps)
Joseph Campanella
Ed Cooper (8 eps)
Charles Siebert
Jerry Davenport (6 eps)
Scott Colomby
Cliff Randall (6 eps)
John Hillerman
Mr. Connors (6 eps)
William Kirby Cullen
Chuck Butterfield (5 eps)
Howard Morton
Hal Butterfield (4 eps)
K Callan
Alice Butterfield (4 eps)
Claudette Nevins
Marge Royer (3 eps)
Thom Bray
Hal (3 eps)
Jerry Houser
Jeff (3 eps)
K.C. Martel
Jason / Bernie Danner (2 eps)
Dick O'Neill
Orville (2 eps)
Nedra Volz
Emily (2 eps)
Angus Duncan
Father Latwell (2 eps)
Marie Reynolds
Polly Jackson (1 eps)
Tish Smiley
Sally (1 eps)
Tom Fitzsimmons
Dr. Donnie Blanchard (1 eps)
Robby Benson
Ken (1 eps)
Melonie Magruder
Messenger (1 eps)
Rosalind Chao
Gloria (1 eps)
Susan Richardson
Eloise (1 eps)
Gary Dontzig
Craig Simmons (1 eps)
Anne Seymour
Estelle Cooper (1 eps)
Van Johnson
Gus Webster (1 eps)
Priscilla Morrill
Estelle Cooper (1 eps)
John Ericson
Clint Wilkens (1 eps)