Wagner Moura
Pablo Escobar (10 eps)
Pedro Pascal
Javier Peña (10 eps)
Boyd Holbrook
Steve Murphy (10 eps)
Joanna Christie
Connie Murphy (10 eps)
Maurice Compte
Horacio Carrillo (10 eps)
Paulina Gaitán
Tata Escobar (10 eps)
Stephanie Sigman
Valeria Velez (10 eps)
Diego Cataño
La Quica (10 eps)
Jorge A. Jimenez
Poison (10 eps)
Juan Pablo Raba
Gustavo Gaviria (10 eps)
Raúl Méndez
Cesar Gaviria (10 eps)
Bruno Bichir
Fernando Duque (10 eps)
Luis Guzmán
José Rodríguez Gacha (10 eps)
Paulina García
Hermilda Gaviria (7 eps)
Ana de la Reguera
Elisa Alvaro (5 eps)
André Mattos
Jorge Luis Ochoa (1 eps)
Roberto Urbina
Fabio Ochoa (1 eps)
Juan Riedinger
Carlos Lehder (1 eps)
Richard T. Jones
Agent DEA (1 eps)
A.J. Buckley
Kevin Brady (1 eps)
Luis Gnecco
La Cucaracha (1 eps)
Jon Ecker
The Lion (1 eps)
Ariel Sierra
Sure Shot (1 eps)
Julián Díaz
El Negro (1 eps)
Carolina Gaitán
Marta Ochoa (1 eps)
Jorge Monterrosa
Trujillo (1 eps)