Anna Faris
Christy Plunkett (22 eps)
Allison Janney
Bonnie Plunkett (22 eps)
Jaime Pressly
Jill Kendall (22 eps)
Mimi Kennedy
Marjorie Armstrong-Perugian (22 eps)
Beth Hall
Wendy Harris (22 eps)
William Fichtner
Adam Janikowski (22 eps)
Michael DiMente
Bruce (4 eps)
Wendie Malick
Danielle (2 eps)
Jonny Coyne
Victor Perugian (2 eps)
Don McManus
Steve (2 eps)
Julia Lester
Emily (2 eps)
Amy Hill
Beverly (2 eps)
Leonard Roberts
Ray (2 eps)
Mary Pat Gleason
Mary (2 eps)
Lauri Johnson
Beatrice (2 eps)
Bradley Whitford
Mitch (1 eps)
Missi Pyle
Natasha (1 eps)
Chris L. McKenna
Derek (1 eps)
Monica Young
Cheryl (1 eps)
Ayo Sorrells
Mike (1 eps)
John-Michael Carlton
Josh (1 eps)
Rosie O'Donnell
Jeanine (1 eps)
Jennifer Taylor
Alissa (1 eps)
Dan Aho
Roger (1 eps)
Diane Delano
Leslie (1 eps)
Mary-Pat Green
Susie (1 eps)
Christopher Goodman
Waiter (1 eps)
Sara Rue
Candace (1 eps)
Joey Rich
Customer (1 eps)
Kevin Daniels
Officer Bill (1 eps)
Jason Olive
Paul (1 eps)
Andrew James Allen
Jackson (1 eps)
Andrew Ortega
Jimmy (1 eps)
Tim Bagley
Dr. LaSalle (1 eps)
Jack McGee
Frank (1 eps)
Louise Claps
Linda (1 eps)
J.J. Boone
Charlotte (1 eps)
Jennifer Chang
Nurse (1 eps)
Christina Moore
Camille (1 eps)
Ivan Hernandez
Officer Darren (1 eps)
Chris Pratt
Nick (1 eps)
John O'Brien
Waiter (1 eps)
Amy Farrington
June (1 eps)
David James Elliott
Joe (1 eps)
Claudia Choi
Woman (1 eps)
Marcus Toji
Walter (1 eps)
Carrie Armstrong
Carla (1 eps)
Doc Farrow
Sam (1 eps)
Chip Chinery
Dave (1 eps)
Carlease Burke
Nurse Patricia (1 eps)
Dana L. Wilson
Barbara (1 eps)
Rachel Winfree
Judith (1 eps)
David Trice
Man (1 eps)
Neil Ross
Announcer (voice) (1 eps)
Bret Harrison
Brad (1 eps)
Nathan Anderson
Guy (1 eps)
John Benjamin Hickey
Dr. Sellers (1 eps)
Yeardley Smith
Enid (1 eps)
David Anthony Higgins
George (1 eps)
Nicole Sullivan
Leanne (1 eps)
Charles Robinson
Mr. Munson (1 eps)