Keith Ferguson
Megamind (voice) (8 eps)
Laura Post
Roxanne Ritchi (voice) (8 eps)
Josh Brener
Ol' Chum (voice) (8 eps)
Maya Tuttle
Keiko Morita (voice) (8 eps)
Emily Tunon
Lady Doppler (voice) (8 eps)
Talon Warburton
Lord Nighty-Knight (voice) (8 eps)
Scott Adsit
Pierre Pressure (voice) (8 eps)
Chris Sullivan
Behemoth (voice) (8 eps)
Tony Hale
Mel / Mr. Donut (voice) (8 eps)
Jeanine Mason
Christino Christo (voice) (8 eps)
Adam Lambert
Machiavillain (voice) (8 eps)