Michael Sheen
William Masters (12 eps)
Lizzy Caplan
Virginia Johnson (12 eps)
Caitlin FitzGerald
Libby Masters (12 eps)
Nicholas D'Agosto
Dr. Ethan Haas (12 eps)
Teddy Sears
Dr. Austin Langham (12 eps)
Heléne Yorke
Jane Martin (10 eps)
Beau Bridges
Dr. Barton Scully (9 eps)
Julianne Nicholson
Dr. Lillian DePaul (7 eps)
Rose McIver
Vivian Scully (6 eps)
Cole Sand
Henry Johnson (6 eps)
Kayla Madison
Tessa Johnson (6 eps)
Allison Janney
Margaret Scully (6 eps)
Jorie Stern
Nurse (uncredited) (4 eps)
Finn Wittrock
Dale (4 eps)
Ann Dowd
Estabrooks Masters (3 eps)
Garrett M. Brown
Chancellor Fitzhugh (3 eps)
Nicholle Tom
Maureen (2 eps)
Sara Rae Foster
Dottie (2 eps)
Ellen Wroe
Ginger (2 eps)
William Nicol
Operating Doctor #2 (2 eps)
Alan Ruck
Psychiatrist (2 eps)
Logan Donovan
Travis Banks (2 eps)
Adam Silver
Tim Deasy (2 eps)
Joan Severance
Leona (2 eps)
Mary Passeri
Jean Richards (2 eps)
Susie Schelling
OR Nurse (2 eps)
Marlane Barnes
Gladys (2 eps)
Jennifer Holloway
Ramona (2 eps)
Anne Griffin
Kathleen (2 eps)
James Eckhouse
Dr. Chuck Ingram (2 eps)
Tim Ransom
Dr. Rish (2 eps)
Kandis Fay
Pam (2 eps)
Mather Zickel
George Johnson (2 eps)
Roslyn Ruff
Josephine May (1 eps)
Margo Martindale
Miss Horchow (1 eps)
Steve Rosen
Ernie Turk (1 eps)
Johanna Day
Advisor (1 eps)
Mary Jo McConnell
Desk Nurse (1 eps)
Jeffrey C. Hawkins
OR Doctor #1 (1 eps)
Linda Marie Larson
Lois Tupps (1 eps)
Danae Nason
Assisting Nurse #1 (1 eps)
Mark Rosing
Anesthesiologist (1 eps)
Phil McGlaston
Worker (1 eps)
Duncan Bindbeutel
Doctor at Party (uncredited) (1 eps)
Roy Pollack
Upscale Party Goer (uncredited) (1 eps)
Elysia Richards
Nurse (uncredited) (1 eps)
Tanya Wheelock
College Student (uncredited) (1 eps)
Matthew Dean Wood
Party Guest (uncredited) (1 eps)
April Parker Jones
Mrs. Katcher (1 eps)
Ruby Lewis
Connie (1 eps)
Kristin Slaysman
Bernadette (1 eps)
Susan-Kate Heaney
Shirley (1 eps)
Khali Macintyre
Claire (1 eps)
Debbie Jaffe
Nurse Grand (1 eps)
Clark Moore
Officer Burt (1 eps)
Doug Hurley
John (uncredited) (1 eps)
Mae Whitman
Patient (1 eps)
Lauren Weedman
Quadruplets' Mother (1 eps)
Bobby Campo
Carl (1 eps)
Simone Carter
Arda (1 eps)
Clark Freeman
Operating Doctor #1 (1 eps)
Natasha Sims
Operating Nurse (1 eps)
Ori Kalmus
Reporter (1 eps)
Casey Dolkas
Photographer (1 eps)
Cleo Fraser
Vivian Scully (1 eps)
Adam Maurer
Med Student (uncredited) (1 eps)
Barrett Perlman
Prostitute (uncredited) (1 eps)
Evie Ryland
Nursery Visitor (uncredited) (1 eps)
Leah Shaw
Prostitute (uncredited) (1 eps)
Michael Mantell
Byron (1 eps)
Martha Hackett
Shirley (1 eps)
Emily Bridges
Velma (1 eps)
Dean Chekvala
Mr. Zelinsky (1 eps)
Kira Sternbach
Marjorie (1 eps)
Gabe O'Mara
Daniel Zelinsky (1 eps)
Monica Hewes
Sophia Zelinsky (1 eps)
Michael Tower
Doug (1 eps)
Carolyn Crotty
Marilyn (1 eps)
Jed Sura
Assistant Doctor (1 eps)
Tony Robinette
Nerdy Man (1 eps)
Charlotte Chanler
Woman (1 eps)
Chris Degner
Working Class Man (1 eps)
Sarah Allyn Bauer
Young Woman (1 eps)
Faleena Hopkins
Young Estabrooks (1 eps)
Christina Cannarella
Delivery Nurse (1 eps)
Christian O'Brien
Guest (uncredited) (1 eps)
Joseph Lyle Taylor
Stan (1 eps)
Kyle Jones
Glenn (1 eps)
Emily Davenport
Patty (1 eps)
Romina Bovolini
F-102 (1 eps)
Cheryl Bricker
Subject 096 (1 eps)
Mike Peebler
Anesthesiologist (1 eps)
Shaun Rylee
Scully Family Friend (uncredited) (1 eps)
Barry Bostwick
Morris (1 eps)
Ann Cusack
Harriet (1 eps)
Caroline Lagerfelt
Barb (1 eps)
Leah Costello
Louise (1 eps)
Rachel Kimsey
Nessie Lawson (1 eps)
Helen Wilson
Dr. Anna Freud (1 eps)
Kirsten Kollender
Receptionist (1 eps)
Eileen Grubba
Lucille (1 eps)
Jarard Kings
Passenger (1 eps)
John Pollono
David Haas (1 eps)
Brian R. Norris
Jake Prescott (1 eps)
Shanna Collins
JoBeth Prescott (1 eps)
Micah A. Hauptman
Kyle (1 eps)
Pepper Binkley
Adelaide (1 eps)
Michael Dunn
Car Dealer (1 eps)
Mary Catalano
Myrtle (1 eps)
Alex Chansky
Thug #1 (1 eps)
Craig Baxley Jr
Thug #2 (1 eps)
Flex Alexander
Walter (1 eps)
Brit Shaw
Colleen (1 eps)
Gary Kraus
Dennis (1 eps)
Braden Moran
Doctor in Lecture (1 eps)
Doug McKeon
Reverend Peter Mayfair (1 eps)
Rob Kerkovich
Jeremy (1 eps)
Bennet Guillory
Eustace (1 eps)
Claire van der Boom
Shirley (1 eps)
Bug Hall
Schacter (1 eps)
Gil McKinney
Charles (1 eps)
Kate Fuglei
Marie (1 eps)
Jeff Doucette
Mr. Langshaw (1 eps)
Jamie Landau
Mason (1 eps)
Michael Yavnielli
Jacob (1 eps)
Rick Marcus
Roger (1 eps)
Olivia May
Peep Show Woman (1 eps)
Spencer Garrett
Beckett (1 eps)
Devlin Wilder
Affluent Gentleman (uncredited) (1 eps)
Anne Dudek
Rosalie (1 eps)
Betsy Zajko
Ruby (1 eps)
Molly Hagan
Sybil (1 eps)
Zak Barnett
Ted (1 eps)
Ashley Johnson
Flora Banks (1 eps)
Carrie Wiita
Penny (1 eps)
Nealla Gordon
Nurse Lang (1 eps)
Milissa Sears
Audrey (1 eps)
Kelly Lynn Warren
Nurse Gwynne (1 eps)
Bethany Dwyer
Nurse Pratt (1 eps)
Christopher Clausi
Bar Single (uncredited) (1 eps)
Dean Wayne
Bus Passenger (uncredited) (1 eps)
Michael Cassidy
Dr. Malcolm Toll (1 eps)
Amanda Jane Cooper
Sissy (1 eps)
Rebecca Staab
Enid (1 eps)
Rebecca Larsen
Betsy (1 eps)
Liv von Oelreich
Diana (1 eps)
Patty Cornell
Louise (1 eps)
William Charles Mitchell
Staffer (1 eps)
Cheyenne Wilbur
Bus Passenger (1 eps)
Jason Kravits
Doctor (1 eps)
Robert Joy
Dr. Ellenberg (1 eps)
Linara Washington
Lini (1 eps)
Blake Robbins
Security Guard Brown (1 eps)
Jocelyn Ayanna
Bitsy (1 eps)
Wiley M. Pickett
Colonel Stapp (1 eps)
George Jonson
Major Simons (1 eps)
Kyla Deaver
Katie Langham (1 eps)
Will Jennings
Sam Langham (1 eps)
Evan Arnold
Dr. Ditmer (1 eps)
Greg Grunberg
Gene Moretti (1 eps)
Elizabeth Bogush
Elise Langham (1 eps)
Brian Howe
Sam Duncan (1 eps)