Chloe Bennet
Daisy 'Skye' Johnson / Quake (13 eps)
Clark Gregg
Sarge (13 eps)
Elizabeth Henstridge
Jemma Simmons (13 eps)
Ming-Na Wen
Melinda May (13 eps)
Henry Simmons
Alphonso 'Mack' Mackenzie (13 eps)
Natalia Cordova-Buckley
Elena 'Yo-Yo' Rodriguez (13 eps)
Jeff Ward
Deke Shaw (13 eps)
Iain De Caestecker
Leo Fitz (13 eps)
Joel Stoffer
Enoch (9 eps)
Karolina Wydra
Izel (7 eps)
Brooke Williams
Snowflake (7 eps)
Briana Venskus
Piper (7 eps)
Christopher James Baker
Malachi (6 eps)
Winston James Francis
Jaco (6 eps)
Maximilian Osinski
Davis (6 eps)
Matt O'Leary
Pax (5 eps)
Barry Shabaka Henley
Marcus Benson (5 eps)
Scott Kruse
Boyle (4 eps)
T.J. Alvarado
Toad (4 eps)
Shainu Bala
Trevor Khan (4 eps)
Christian Ochoa
Baal-Gad (3 eps)
Jan Uddin
Isaiah (3 eps)
Sherri Saum
Atarah (3 eps)
Lucas Bryant
Agent Keller (3 eps)
Xavier Jiménez
Tinker (2 eps)
Ski Carr
Montalban (2 eps)
Portia Bartley
Kaya (2 eps)
Teodora Marcella
Lindsay (2 eps)
Coy Stewart
Flint (2 eps)
Geri-Nikole Love
Quinjet Pilot (1 eps)
Levi Meaden
Agent Fox (1 eps)
Glenn Keogh
Agent Keller (1 eps)
Anthony Michael Hall
Mister Kitson (1 eps)
Maurissa Tancharoen
Sequoia (1 eps)
Paul Telfer
Viro (1 eps)
Sola Bamis
Dana (1 eps)
Clark Middleton
Pretorious Pryce (1 eps)
Douglas Bennett
Long-Haired Gambler (1 eps)
Bubba Ganter
Security Guard (1 eps)
Charlotta Mohlin
Greeter (1 eps)
Galen Howard
Greaseball (1 eps)
Robb Derringer
Thomas (1 eps)
Ava Mireille
Young Jemma Simmons (1 eps)