Téa Leoni
Elizabeth McCord (22 eps)
Tim Daly
Henry McCord (22 eps)
Bebe Neuwirth
Nadine Tolliver (22 eps)
Zeljko Ivanek
Russell Jackson (22 eps)
Patina Miller
Daisy Grant (22 eps)
Erich Bergen
Blake Moran (22 eps)
Sara Ramirez
Kat Sandoval (22 eps)
Wallis Currie-Wood
Stephanie 'Stevie' McCord (22 eps)
Evan Roe
Jason McCord (22 eps)
Kathrine Herzer
Alison McCord (22 eps)
Sebastian Arcelus
Jay Whitman (22 eps)
Geoffrey Arend
Matt Mahoney (22 eps)
Nicholas Guest
President Salnikov (1 eps)
Anthony Thomas
Major Jennings (1 eps)
Keren Dukes
Marine (1 eps)
Christine Chang
Shindy (1 eps)
Charles Socarides
Scott Goodman (1 eps)
Vandit Bhatt
Tech (1 eps)
Geoffrey Dawe
Carl (1 eps)
Elpidia Carrillo
President Daphne Tejeda (1 eps)