Brie Larson
Elizabeth Zott (8 eps)
Lewis Pullman
Calvin Evans (8 eps)
Aja Naomi King
Harriet Sloane (8 eps)
Stephanie Koenig
Fran Frask (8 eps)
Patrick Walker
Curtis Wakely (8 eps)
Marc Evan Jackson
Dr. Leland Mason (6 eps)
Derek Cecil
Dr. Robert Donatti (5 eps)
Kevin Sussman
Walter Pine (5 eps)
Thomas Mann
Alfred Boryweitz (5 eps)
Paul James
Charlie Sloane (5 eps)
Alice Halsey
Madeline 'Mad' Zott (5 eps)
Rainn Wilson
Phil Lebensmal (4 eps)
Andy Daly
Dr. Richard Price (4 eps)
Joshua Hoover
Anthony Powers (4 eps)
Yasir Lafond
James 'Junior' Sloane (4 eps)
Amentii Sledge
Linda Sloane (4 eps)
Adam Bartley
Scientist (3 eps)
Brandon Gibson
Tom Clemens (3 eps)
Robert Alan Beuth
Frank Marsten (3 eps)
Sigi Ravet
Laurel Moore (3 eps)
Debbie Pollack
Louise (3 eps)
Laura Siegel
Bertha Clifton (3 eps)
Gregg Brown
Director (3 eps)
John Alton
Stage Manager (3 eps)
Isaac Jay
Production Assistant / Harry the PA (3 eps)
James Gleason
Chairman of the Board (3 eps)
Beau Bridges
Harry Wilson (3 eps)
Shoo Shoo Parsells
Amanda Pine (3 eps)
Alana Gay
Linda Sloane (3 eps)
Hero Hunter
James 'Junior' Sloane (3 eps)
Joy Jacobson
Shari (3 eps)
Ali Kinkade
Jenny Marie Kay (2 eps)
Caroline Cole
Charlene Ogilvy (2 eps)
Caryn West
Mrs. Mudford (2 eps)
Constance Ejuma
Agnes (2 eps)
Keena Ferguson
Rhoda (2 eps)
Catherine Hyslop
Lena (2 eps)
Lauren Cook
Rebecca (2 eps)
Tristen MacDonald
Mrs. Fillis (2 eps)
Hannah Horton
Walter's Secretary / Walter's Secretary - Joan (2 eps)
Adam O'Byrne
Bishop (2 eps)
Ashley Monique Clark
Martha Wakely (2 eps)
Alyssa Preston
Wilson's Secretary (2 eps)
Valentina Garcia
Nancy Donatti (1 eps)
Eileen Álvarez
Hair Stylist (1 eps)
Tate Ellington
Dr. Bates (1 eps)
Michael James Bell
Highway Suit (1 eps)
Troy Vincent
UCLA Professor (1 eps)
Pamela Shafer
Associate Dean (1 eps)
Kent Hagen
City Council Chairman (1 eps)
B.J. Novak
Six-Thirty (voice) (1 eps)
Jake Short
Ralph Bailey (1 eps)
Nicolas Coster
Paul Astor (1 eps)
Barry Livingston
Pastor (1 eps)
Alex Boling
Oocyte Chemist (1 eps)
Lee Eisenberg
Funeral Director (1 eps)
Brian Leckner
Businessman (1 eps)
Cameron Fay
Police Officer (1 eps)
Aaron Coleman
Harriet's Colleague (1 eps)
Phoebe Kuhlman
Nurse (1 eps)
Kandis Fay
New Mother (1 eps)
Jonney Ahmanson
Baseball Fan (1 eps)
Steven Pritchard
Whiskey Guy (1 eps)
Tyler Beardsley
Magazine Shredder (1 eps)
Sherry Larson
Gerta Borgnino (1 eps)
Danny Brown
Jodie (1 eps)
Maya Malan-Gonzalez
Wailing Woman (1 eps)
Jeff Marlow
Bank Manager (1 eps)
Casey Feigh
Moving Supervisor (1 eps)
Indiana Elle
Bully #1 (1 eps)
Lola Kelly
Housewife (1 eps)
Amanda Walsh
Waitress (1 eps)
Todd Aaron Brotze
Consultant (1 eps)
Alex Staggs
Sound Mixer (1 eps)
Julianne Buescher
Secretary (1 eps)
Kameron Brummer
Tommy (1 eps)
Daniele O'Loughlin
Harried Mother (1 eps)
Dexter Alvarez
Crazy Kid #1 (1 eps)
Luke Alvarez
Crazy Kid #2 (1 eps)
Nathan Caywood
Male Audience Member #1 (1 eps)
Jonathan Fishman
Male Audience Member #2 (1 eps)
Herbert Russell
Male Audience Member #3 (1 eps)
James Vincent
Male Audience Member #4 (1 eps)
Tammy Caplan
Female Audience Member #1 (1 eps)
Jessy Greer
Female Audience Member #2 (1 eps)
Jackson Kelly
John Zott (1 eps)
Jon Fletcher
Ezra Zott (1 eps)
Ridley Haitkin
Young Elizabeth Zott (1 eps)
Danielle Hoetmer
Iris Zott (1 eps)
Ben Shields
Mayor Van Veen (1 eps)
Tunisia Hardison
Marge (1 eps)
Annie O'Donnell
Mrs. Eugenia Waterhouse (1 eps)
Chanté Bowser
Suz (1 eps)
Steven Connor
Jameson (1 eps)
Carson Zone
Mayor's Son (1 eps)
Meredith Jackson
Mayor's Wife (1 eps)
Vaughndio Forbes
Sanford (1 eps)
Dan Sachoff
Reporter (1 eps)
Gaye Coffman
Librarian (1 eps)
Laura Hurst
Shirley (1 eps)
David Lee Hess
Rheumy Eyes (1 eps)
Lon Gowan
Head Cop Stunt #1 (1 eps)
Kim D'Armond
Audience Member #1 (1 eps)
Kyley Koeth
Audience Member #2 (1 eps)
Carrie Weisberg
Audience Member #3 (1 eps)
Christina Childress
Stunt Protestor #1 (1 eps)
Caden Dragomer
Young Calvin Evans (1 eps)
Myles Cranford
Clarence Wakely (1 eps)
Mara Hernandez
Jesse (1 eps)
Taylor Foster
Jewelry Store Employee (1 eps)
Avery Bilz
Mail Boy (1 eps)
Vincent Stalba
Scientific American Photographer (1 eps)
Catherine Adell
Sister Margaret (1 eps)
Natalie Wetta
Sister Mary Lou (1 eps)
Emily Happe
Sister Beth Ann (1 eps)
Kaido Lee Roberts
Fred (1 eps)
Griffen Campbell
Lester (1 eps)
Rosemarie DeWitt
Avery Parker (1 eps)
Ronin Lee
Paralegal (1 eps)
Greg Benson
Kenneth (1 eps)
Belle Starr
Sixth Grade Girl (1 eps)
Sandra Kate Burck
Secretary's Friend (1 eps)
Darin Toonder
Committee Chair (1 eps)
David Bickford
Councilman Sommers (1 eps)
Sam Bixby
Valet (1 eps)
Maddie Levy
Young Avery (1 eps)
Sue Zen Chew
Student #1 (1 eps)
Sarah Glassman
Student #2 (1 eps)