Gabriel Byrne
Dr. Paul Weston (106 eps)
Uzo Aduba
Dr. Brooke Taylor (24 eps)
Dianne Wiest
Dr. Gina Toll (16 eps)
Michelle Forbes
Kate Weston (14 eps)
Blair Underwood
Alex Prince (9 eps)
Mia Wasikowska
Sophie (9 eps)
Josh Charles
Jake (8 eps)
Embeth Davidtz
Amy (8 eps)
Amy Ryan
Adele Brouse (8 eps)
Joel Kinnaman
Adam (8 eps)
Melissa George
Laura Hill (8 eps)
Alex Wolff
Max Weston (7 eps)
Hope Davis
Mia Nesky (7 eps)
Alison Pill
April (7 eps)
Aaron Grady Shaw
Oliver (7 eps)
John Mahoney
Walter Barnett (7 eps)
Irrfan Khan
Sunil Sanyal (7 eps)
Debra Winger
Frances Greer (7 eps)
Dane DeHaan
Jesse D'Amato (7 eps)
Sherri Saum
Bess (6 eps)
Russell Hornsby
Luke (6 eps)
Anthony Ramos
Eladio Restrepo (6 eps)
John Benjamin Hickey
Colin Craft (6 eps)
Quintessa Swindell
Laila Green (6 eps)
Liza Colón-Zayas
Rita Ortiz (6 eps)
Mae Whitman
Rosie Weston (5 eps)
Laila Robins
Tammy Meswick (4 eps)
Glynn Turman
Alex Prince Sr. (4 eps)
Charlayne Woodard
Rhonda (4 eps)
Julia Campbell
Olivia (2 eps)
Lauren Hodges
Natalie Barnett (2 eps)
Max Burkholder
Max Weston (2 eps)
Susan Misner
Wendy (2 eps)
Sonya Walger
Julia (2 eps)
Peter Horton
Zach (1 eps)
Jake Richardson
Ian Weston (1 eps)
Chris Heuisler
Man (1 eps)
Keith Nobbs
Eli (1 eps)
Amanda Axelrod
Melissa (1 eps)
Samrat Chakrabarti
Arun Sanyal (1 eps)
Dendrie Taylor
Marisa (1 eps)
Joseph Siravo
Roberto D'Amato (1 eps)
Brian Shortall
Darren (1 eps)
Patrick Cavanaugh
Pizza Delivery Guy (1 eps)
Sonya Maddox
Michaela Prince (1 eps)
Drew Matthews
Roy Prince (1 eps)
David Norona
Daniel Alterio (1 eps)
Lawrence LeJohn
Man at Funeral (1 eps)
Mike Doyle
Bennett (1 eps)
Michael Gargani
Henry (1 eps)
Bruce-Robert Serafin
Train Passenger (1 eps)
Shawna Christensen
Woman (1 eps)
Chad Gittens
Courier (1 eps)
Madeline Zima
Karla (1 eps)
James A. Stephens
Paul's Father (1 eps)
Jake Choi
Notary Public (1 eps)
Jacquelyn Reingold
Anita (1 eps)
Cassandra Palacio
Elaine (1 eps)
Ashleigh Banfield
Ashleigh Banfield (1 eps)
James Lloyd Reynolds
Steve (1 eps)
Robyn Rikoon
Izzy (1 eps)
Rachel Brosnahan
Eating Disorder Girl (1 eps)
Guy Boyd
Doctor (1 eps)
Natalie Carter
Prison guard (1 eps)
Gilbert Cruz
Prison guard (1 eps)
Curtis Shumaker
Prison guard (1 eps)