Nick Kroll
Maury Beverley (voice) (44 eps)
Maya Rudolph
Connie LaCienega (voice) (28 eps)
Brandon Kyle Goodman
Walter Las Palmas (voice) (23 eps)
Keke Palmer
Rochelle Hillhurst (voice) (21 eps)
David Thewlis
Lionel St. Swithens (voice) (21 eps)
Pamela Adlon
Sonya Poinsettia (21 eps)
Joe Wengert
Joe (voice) (21 eps)
Aidy Bryant
Emmy Fairfax (voice) (20 eps)
Randall Park
Pete Doheny (voice) (20 eps)
Hugh Jackman
Dante (voice) (8 eps)
John Gemberling
Tyler Pico (voice) (6 eps)
Gil Ozeri
Gil (voice) (6 eps)
Niecy Nash-Betts
Hope (voice) (6 eps)
Cole Escola
Montel (voice) (6 eps)
Ali Wong
Becca Lee (voice) (5 eps)
Miley Cyrus
Van the Logic Rock (voice) (5 eps)
Mike Birbiglia
Barry (voice) (4 eps)
Florence Pugh
Sarah Crumbhorn (voice) (4 eps)
Ashley London
(voice) (3 eps)
Ahmed El-Mawas
Amir (voice) (3 eps)
Harvey Guillén
José the Spider Receptionist (voice) (3 eps)
Tim Robinson
Doug (voice) (3 eps)
Eugene Levy
Paul Crumbhorn (voice) (3 eps)
James III
Cat Stevens (voice) (2 eps)
Godfrey
(voice) (2 eps)
Chris O'Dowd
Flanny the Lovebug (voice) (2 eps)
Nidah Barber
Yara (voice) (2 eps)
Ulka Simone Mohanty
Nabilah (voice) (2 eps)
Maria Bamford
Tito the Anxiety Mosquito (voice) (2 eps)
Josie Totah
Natalie (voice) (2 eps)
Thandiwe Newton
Mona (voice) (1 eps)
Mark Rivers
(voice) (1 eps)
Casey Wilson
Empathy Mulholland (voice) (1 eps)
James Adomian
Becca's Baby's Need Demon (voice) (1 eps)
Helen Mirren
Shame Wizard Rita St. Swithens (voice) (1 eps)
Max Silvestri
(voice) (1 eps)
Ariana DeBose
Danielle (voice) (1 eps)
Sabrina Jalees
Nadia (voice) (1 eps)
John Mulaney
Andrew Glouberman (voice) (1 eps)
Mitra Jouhari
(voice) (1 eps)
Kayvan Novak
Arsalan (voice) (1 eps)
Lupita Nyong'o
Shame Wizard Asha (voice) (1 eps)
Janelle Monáe
Claudia (voice) (1 eps)
Bobby Cannavale
Gavin Reeves (voice) (1 eps)
Rosie Perez
Petra the Ambition Gremlin (voice) (1 eps)