Andre Braugher
Dr. Ben Gideon (21 eps)
Ravi Kapoor
Dr. Sid Shandar (21 eps)
Eric Dane
Dr. Wyatt Cooper (21 eps)
Rhona Mitra
Dr. Alejandra Ollie Klein (21 eps)
Hamish Linklater
Dr. Bruce Cherry (21 eps)
Jascha Washington
Eli Gideon (21 eps)
Rubén Blades
Dr. Max Cabranes (21 eps)
Russell Hornsby
Dr. Aaron Boies (21 eps)
Kevin J. O'Connor
Dr. Michael Pirandello (21 eps)
Pamela Dunlap
Marge (1 eps)
Rosalind Chao
Claire Hines (1 eps)