Billy West
Fry / Professor Farnsworth / Zoidberg / Zapp Brannigan (voice) (12 eps)
Katey Sagal
Leela (voice) (12 eps)
John DiMaggio
Bender (voice) (12 eps)
Tress MacNeille
Mom (voice) (12 eps)
Maurice LaMarche
Morbo / Kif Kroker (voice) (12 eps)
Lauren Tom
Amy Wong (Voice) (12 eps)
Phil LaMarr
Hermes Conrad (voice) (12 eps)
David Herman
Scruffy (voice) (12 eps)
Frank Welker
Nibbler (voice) (12 eps)
Walter Koenig
Walter Koenig (voice) (1 eps)
Sigourney Weaver
Planet Express Ship (voice) (1 eps)
Leonard Nimoy
Leonard Nimoy's Head (Voice) (1 eps)
William Shatner
William Shatner (voice) (1 eps)
Jonathan Frakes
Jonathan Frakes (voice) (1 eps)
Nichelle Nichols
Nichelle Nichols' Head (voice) (1 eps)
Bob Uecker
Bob Uecker (voice) (1 eps)
Hank Aaron
Hank Aaron (voice) (1 eps)
Coolio
Kwanzaabot (voice) (1 eps)
George Takei
George Takei's Head (voice) (1 eps)
Lucy Liu
Lucy Liu's Head (voice) (1 eps)
Dawnn Lewis
Jackie Anderson (voice) (1 eps)