Nathan Fillion
Mal Reynolds (11 eps)
Gina Torres
Zoë Washburne (11 eps)
Alan Tudyk
Hoban Washburne (11 eps)
Morena Baccarin
Inara Serra (11 eps)
Adam Baldwin
Jayne Cobb (11 eps)
Jewel Staite
Kaylee Frye (11 eps)
Sean Maher
Simon Tam (11 eps)
Summer Glau
River Tam (11 eps)
Ron Glass
Derrial Book (11 eps)
Jeff Ricketts
Man (2 eps)
Dennis Cockrum
Blue Glove Man #2 (2 eps)
Zac Efron
Young Simon (2 eps)
Gerard J. Reyes
Bodyguard / Shopper (uncredited) (2 eps)
Mark Sheppard
Badger (2 eps)
Christina Hendricks
Saffron (2 eps)
Damion Poitier
Henchman (1 eps)
Tom Towles
Lund (1 eps)
Andrew Bryniarski
Crow (1 eps)
Gregg Henry
Sheriff Bourne (1 eps)
Doug Savant
Commander Harken (1 eps)
Lancer Dean Shull
Radio Operator (1 eps)
Benito Martinez
Boss (1 eps)
Erik Passoja
Bree (1 eps)
Bob Fimiani
Elder Gommen (1 eps)
Daniel Bess
Mudder (1 eps)
Kevin Gage
Stitch Hessian (1 eps)
Zachary Kranzler
Fess Higgins (1 eps)
Edward Atterton
Atherton Wing (1 eps)
Larry Drake
Sir Warwick Harrow (1 eps)
Carl Bresk
Wright (1 eps)
Larry Pennell
Murphy (1 eps)
William Converse-Roberts
Gabriel Tam (1 eps)
John Thaddeus
Stark (1 eps)
Gary Werntz
Patron (1 eps)
Andy Rolfes
Marcus Grange / Older Grange (1 eps)
Matthew Ferreira
Nathaniel Grange / Younger Grange (1 eps)
Blake Robbins
Agent McGuinness (1 eps)
Tom Virtue
Pompous Doctor (1 eps)
Roma Chugani
Receiving Doctor (1 eps)
Katherine Kendall
The Councillor (1 eps)
Rolando Molina
Bolles (1 eps)
Michael Bentt
Viktor (1 eps)
Richard Brooks
Jubal Early (1 eps)
Andy Umberger
Dortmunder Captain (1 eps)
Philip Sternberg
Inara's Client (1 eps)
Colin Patrick Lynch
Radio Operator (1 eps)
Bonnie Bartlett
Patience (1 eps)
Domingo Vara
Ensign (1 eps)
Stephen O'Mahoney
Dortmunder Man (1 eps)
Gabrielle Wagner
Slave (1 eps)
Valerie Red-Horse
Deputy (1 eps)
Lina Patel
Ensign (1 eps)
Kevin Will
Officer (1 eps)
Eric Lange
Fed (1 eps)
David Reynolds
Henchman (1 eps)
Rene Hamilton
Immigrant Woman (1 eps)
Michelle Ferrara
Immigrant Woman #2 (1 eps)
Alex Stemkovsky
Bandit (1 eps)
Clement Blake
Mudder Elder (1 eps)
John Jabaley
Bartender (1 eps)
Jordan Lund
Foreman (1 eps)
Ronald Craig Williams
Busker (1 eps)
Bob McCracken
Well-Dressed Man (1 eps)
Laura Niemi
Woman (1 eps)
Simon Brooke
Prod (1 eps)
Michael McMillian
Younger Hopeful (1 eps)
Kim Onasch
Banning (1 eps)
Janora McDuffie
Cabott (1 eps)
Casey Piotrowski
Older Farmer (1 eps)
Hunter Cochran
Younger Farmer (1 eps)
Roy Werner
Gentleman (1 eps)
Erica Tazel
Doralee (1 eps)
Michael Nagy
Particularly Dressed Man (1 eps)
Cate Cohen
Crash Team Nurse (1 eps)
Ira Steck
Young Intern (1 eps)
Alex Connie
Patient (1 eps)
John Dunn
The Torturer (1 eps)
Skylar Roberge
Young River (1 eps)
Eddie Adams
Bendis (1 eps)
Melody White
Bellydancer (uncredited) (1 eps)
Rick Williamson
Bar Guy, Henchman (uncredited) (1 eps)
Jared Poe
Ensign (1 eps)
Gary J. Wayton
Rebel Soldier (uncredited) (1 eps)
Heath Russell
Background (uncredited) (1 eps)
Heather Crawford
Mud Man (uncredited) (1 eps)
Tiffany Michelle
Mudwoman (uncredited) (1 eps)
Lon Moriarty
Mudder (uncredited) (1 eps)
Stephen Silberkraus
Mud Farmer (uncredited) (1 eps)
Joshua Grenrock
Porter (1 eps)
Joel Steingold
Head Cop (1 eps)
Ron Ostrow
Commander (1 eps)
Morina Pierce
Ruby (1 eps)
Kelli Wheeler
Blue Sun Spokesmodel (uncredited) (1 eps)
Adam Pilver
Vanilla Husband (scenes deleted) (1 eps)
Johnny Shakespeare
Torture Victim (1 eps)
Jason Van
Man (1 eps)
Jamie McShane
Man (1 eps)
Michael Keyes
Sleeping Soldier (uncredited) (1 eps)
Greg Wendell Reid
Crying Soldier (uncredited) (1 eps)
Rabatan Salem
Hoodlum (uncredited) (1 eps)
Brian J. Williams
Two Fry (uncredited) (1 eps)
Steven Flynn
Captain Sash (1 eps)
Ilia Volok
Marco (1 eps)
Lyle Kanouse
Salesman (1 eps)
Dax Griffin
Bester (1 eps)
Roderick McCarthy
Lacey #1 (1 eps)