Seth MacFarlane
Peter Griffin / Brian Griffin / Stewie Griffin / Glenn Quagmire / Tom Tucker (voice) (12 eps)
Alex Borstein
Lois Griffin / Tricia Takanawa / Loretta Brown / Barbara Pewterschmidt (voice) (12 eps)
Mila Kunis
Meg Griffin (voice) (12 eps)
Seth Green
Chris Griffin (voice) (12 eps)
Mike Henry
Cleveland Brown (voice) (12 eps)
Patrick Warburton
Joe Swanson (voice) (5 eps)
Jeff Bergman
Fred Flintstone / Barney Rubble (voice) (3 eps)
Phil LaMarr
Ellis Boyd 'Red' Redding / Judge (voice) (3 eps)
Lisa Wilhoit
Connie D'Amico (voice) (2 eps)
Lori Alan
Diane Simmons as Imperial Newscaster (voice) (2 eps)
Adam West
Adam West (voice) (2 eps)
Alec Sulkin
Adam Kenneth Handleman / Movie Clerk / Blind Guy (voice) (2 eps)
Jennifer Tilly
Bonnie Swanson (voice) (2 eps)
Ricardo Montalban
The Cow (voice) (1 eps)
Jamie Farr
Jamie Farr (voice) (1 eps)
Pat Crawford Brown
Lead Sanka Dancer (voice) (1 eps)
Amanda Bynes
Anna (voice) (1 eps)
Paula Abdul
Paula Abdul (voice) (1 eps)
Bruce Lanoil
(voice) (1 eps)
Ted McGinley
(voice) (1 eps)
Patrick Stewart
Avery Bullock (voice) (1 eps)
Beverly D'Angelo
Ellen Griswold (voice) (1 eps)
Conway Twitty
Conway Twitty (archive footage) (1 eps)
Helen Reddy
Helen Reddy (voice) (1 eps)
Tamera Mowry-Housley
Esther (voice) (1 eps)
Randy Jackson
Randy Jackson (voice) (1 eps)
Wendy Raquel Robinson
Jackée Harry / Bernice (voice) (1 eps)
Erinn Hayes
Attractive Mom (voice) (1 eps)
Christa Campbell
Elizabeth Shue / Blonde (voice) (1 eps)
Barry Manilow
Barry Manilow (voice) (1 eps)
Chevy Chase
Clark Griswold (voice) (1 eps)
Gabriel Iglesias
Mexican #5 (voice) (1 eps)
Judd Nelson
John Bender (voice) (uncredited) (1 eps)
Evil Dave Letterman
David Letterman (voice) (1 eps)
Phyllis Diller
Thelma Griffin (voice) (1 eps)
Leslie Nielsen
Dr. Rumack (archive footage) (1 eps)
Mick Hucknall
Mick Hucknall (voice) (1 eps)
Rush Limbaugh
Rush Limbaugh / Red 6 (voice) (1 eps)
Drew Barrymore
Jillian Russell (voice) (1 eps)
Harvey Fierstein
Tracy (voice) (1 eps)
Simon Cowell
Simon Cowell (voice) (1 eps)
James Woods
James Woods (voice) (1 eps)
Stephen Stanton
Various (voice) (1 eps)
Mae Whitman
(voice) (1 eps)
Danny Smith
Barber / Customer / Spiderman (voice) (1 eps)
Mark Hentemann
Opie as Tusken Raider (voice) (1 eps)
Bryan Cranston
Dr. Jewish (voice) (1 eps)
Damien Fahey
Dr. Michael Milano (voice) (1 eps)
Rachael MacFarlane
Dorothy Gale / Tracy Flannigan (voice) (1 eps)
Camille Guaty
Lisa / Donna (voice) (1 eps)
Kirker Butler
Various (voice) (1 eps)
Alexandra Breckenridge
Rob's Ex / Spider-Man's Girlfriend (voice) (1 eps)
Chace Crawford
Paul (voice) (1 eps)
Max Burkholder
Kid in Audience (voice) (1 eps)
Chris Sheridan
Cat (voice) (1 eps)
Carrie Fisher
Angela (voice) (1 eps)
John G. Brennan
Mort Goldman (voice) (1 eps)
Nicole Sullivan
Muriel Goldman (voice) (1 eps)
H. Jon Benjamin
Carl (voice) (1 eps)
