Seth MacFarlane
Peter Griffin / Brian Griffin / Stewie Griffin / Glenn Quagmire / Tom Tucker (voice) (20 eps)
Alex Borstein
Lois Griffin / Tricia Takanawa / Loretta Brown / Barbara Pewterschmidt (voice) (20 eps)
Mila Kunis
Meg Griffin (voice) (20 eps)
Seth Green
Chris Griffin (voice) (20 eps)
Mike Henry
Cleveland Brown (voice) (20 eps)
Kevin Michael Richardson
(voice) (9 eps)
Adam West
Adam West (voice) (8 eps)
Mae Whitman
(voice) (6 eps)
Lucas Grabeel
Chadley (voice) (6 eps)
Jennifer Tilly
Bonnie Swanson (voice) (6 eps)
Cary Elwes
Cyrano de Bergerac (voice) (4 eps)
Sanaa Lathan
Muhammad Ali's Wife (voice) (4 eps)
Gary Cole
Principal Shepherd (voice) (4 eps)
Jon Daly
Oliver Platt (voice) (3 eps)
Emily Osment
(voice) (3 eps)
Kate McKinnon
Karen Griffin (Heavy Flo) (voice) (2 eps)
Alexandra Breckenridge
Tori (voice) (2 eps)
Dee Bradley Baker
Maurice (voice) (2 eps)
Ed O'Neill
Bud Swanson (voice) (1 eps)
Belita Moreno
Rosario Vargas (voice) (1 eps)
Jaheem Toombs
Black Kid (voice) (1 eps)
Joe Buck
Baseball Announcer (voice) (1 eps)
Margaret Cho
Hee-Sun (voice) (1 eps)
Sung Kang
Soap Opera Actor (voice) (1 eps)
Ashton Kutcher
Ashton Kutcher (1 eps)
C.S. Lee
Soap Opera Actor (voice) (1 eps)
Kat Purgal
Girl in Commercial (voice) (1 eps)
Tia Carrere
Hawaiian Woman (voice) (1 eps)
Glenn Close
Glenn Close (voice) (1 eps)
Breckin Meyer
(voice) (1 eps)
Mary Kay Place
Farting Lady (voice) (1 eps)
Kathrine Ross
Mayor West's Mother (voice) (1 eps)
Paget Brewster
Gretchen Mercer (voice) (1 eps)
Judd Hirsch
Judd Hirsch (voice) (1 eps)
Michaela Watkins
Girl Pulling Train (voice) (1 eps)
Kerrigan Mahan
(voice) (1 eps)
Ken Marino
Dallas Portland (voice) (1 eps)
Pamela Tyson
Shelby (voice) (1 eps)
Nickie Bryar
Poor Student (voice) (1 eps)
Simon Cowell
Simon Cowell (voice) (1 eps)
Davey Faragher
(voice) (1 eps)
Megan Grano
(voice) (1 eps)
Liam Payne
Liam Payne (voice) (1 eps)
Jim Rash
(voice) (1 eps)
Louis Tomlinson
Louis Tomlinson (voice) (1 eps)
Barkhad Abdi
Abduwali Muse (voice) (1 eps)
Jay Chandrasekhar
Indian Man / Census Taker (voice) (1 eps)
Rob Huebel
Business Meeting Leader (voice) (1 eps)
Anil Kapoor
Prem (voice) (1 eps)
Dan Nainan
Indian Man (voice) (1 eps)
Russell Peters
Padma's Father (voice) (1 eps)
Sendhil Ramamurthy
Indian Man (voice) (1 eps)
Sheetal Sheth
Padma (voice) (1 eps)
Heléne Yorke
(voice) (1 eps)
Carl Reiner
Old Man (voice) (1 eps)
Jonathan Morgan Heit
Amusement Park Ride Operator (voice) (1 eps)
John Mellencamp
John Mellencamp (1 eps)
Reese C. Hartwig
Boy / Kid (voice) (1 eps)
Josh Robert Thompson
Joe Biden (voice) (1 eps)
Rolando Molina
Cellmate (voice) (1 eps)
Ted Jessup
Adam Sandler (voice) (1 eps)
Chad L. Coleman
African Gunman (voice) (1 eps)
Jerry Lambert
Sex Offender (voice) (1 eps)
Jay Leno
Mayor Jay Leno (voice) (1 eps)
Julie Hagerty
Carol West (voice) (1 eps)
Christine Lakin
Joyce Kinney (voice) (1 eps)
Max Charles
Water Park Kid (voice) (1 eps)
Nicole Sullivan
Mrs. Abbott (voice) (1 eps)
Christina Milian
Esther (voice) (1 eps)
Carrie Fisher
Angela (voice) (1 eps)
Martha MacIsaac
Patty (voice) (1 eps)
Ava Acres
Girl (voice) (1 eps)
H. Jon Benjamin
Carl (voice) (1 eps)
Neil deGrasse Tyson
Neil deGrasse Tyson (voice) (1 eps)