Noah Wyle
John Carter (22 eps)
Maura Tierney
Abby Lockhart (22 eps)
Mekhi Phifer
Greg Pratt (22 eps)
Alex Kingston
Elizabeth Corday (22 eps)
Goran Visnjic
Luka Kovac (22 eps)
Sherry Stringfield
Susan Lewis (22 eps)
Ming-Na Wen
Jing-Mei Chen (22 eps)
Laura Innes
Kerry Weaver (22 eps)
Troy Evans
Frank Martin (16 eps)
Liza del Mundo
Severa (6 eps)
Glenn Howerton
Nick Cooper (6 eps)
Donal Logue
Chuck Martin (5 eps)
Paul Blackthorne
Jeremy Lawson (5 eps)
Renée Victor
Florina Lopez (5 eps)
Daniel Dae Kim
Ken Sung (4 eps)
Cole Hauser
Steve Curtis (4 eps)
Steven Culp
Dave Spencer (4 eps)
Kali Majors
Sydney Spencer (3 eps)
Joy Bryant
Valerie Gallant (3 eps)
Kyle Egan
Dori Kerns (3 eps)
Bruno Campos
Eddie Dorset (3 eps)
George Cheung
Mr. Chen (3 eps)
Bob Newhart
Ben Hollander (3 eps)
Julianne Nicholson
Jordan (2 eps)
Patrick Kerr
George Deakins (2 eps)
Conni Marie Brazelton
Connie Oligario (2 eps)
Archie Kao
Yuri (2 eps)
John Aylward
Donald Anspaugh (2 eps)
Nicholas D'Agosto
Andy (2 eps)
Maury Sterling
Dr. Nelson (2 eps)
Carla Jimenez
Eloise (2 eps)
Kevin Sussman
Colin (2 eps)
Luis Chávez
Roger (2 eps)
Pamela Sinha
Amira (2 eps)
Frank McRae
Freddie (2 eps)
Lisa Vidal
Sandy Lopez (2 eps)
Sam Sarpong
Antwan (1 eps)
Lilyan Chauvin
Nurse Edna (1 eps)
Khleo Thomas
Brian (1 eps)
Sam Hennings
U.S. Financial Attache Steve Davison (1 eps)
Corbin Allred
Doug (1 eps)
Rob McElhenney
Andy Fesh (1 eps)
Marin Hinkle
Kathy (1 eps)
Ashley Laurence
Campbell (1 eps)
Reiner Schöne
Mr. Garland (1 eps)
Alyson Reed
Ginny (1 eps)
Cameron Dye
Damian's Dad (1 eps)
Alison Elliott
Paula Martin (1 eps)
Bill Macy
Richard Gould (1 eps)
Betsy Brandt
Franny Myers (1 eps)
Amy Hunter
Hannah's Mom (1 eps)
Bellina Logan
Kit (1 eps)
L. Scott Caldwell
Dr. Rabb (1 eps)
Paul Dooley
Henry Lewis (1 eps)
Lee Ryan
Ortho #2 (1 eps)
Niecy Nash-Betts
Judith Anderson (1 eps)
Gavin Fink
Henry Martin (1 eps)
Garikayi Mutambirwa
John Deere Boy (1 eps)
Michael Gregory
Westbrook (1 eps)
Rheagan Wallace
Layla Dering (1 eps)
Ryan Michelle Bathe
Miss Evelyn (1 eps)
Michael Angarano
Zack (1 eps)
Bret Loehr
Matthew (1 eps)
Rhyon Nicole Brown
Erika Crawford (1 eps)
Petrea Burchard
Judge Amoroso (1 eps)
Amy Pietz
Pregnant HIV+ Woman (1 eps)
Jimmie Walker
Jay Jay (1 eps)
Kristin Herrera
Frederika Meehan (1 eps)
Christopher Cousins
Kyle Kolber (1 eps)
Shanelle Gray
Denise (1 eps)
Matt Barr
Billy (1 eps)
Patrick Fischler
Chamber Tech (1 eps)
Jeremy Glazer
Med Student David (1 eps)
Shannon Lucio
Johanna Lambright (1 eps)
Sarah Shahi
Tara King (1 eps)
Julie Ariola
Emily (1 eps)
Larry Sullivan
Martin Pryor (1 eps)
Zac Efron
Bobby Neville (1 eps)
Armin Shimerman
Levine (1 eps)
Ellen Geer
Mrs. Ferguson (1 eps)
Jordan Reid
Susannah (1 eps)
Sasha Mitchell
Bartender (1 eps)
Richard Kline
Arnie Nadler - Risk Assessment Expert (1 eps)
Nadege August
Mrs. Lemonier (1 eps)
Eugene Byrd
James Connor (1 eps)
Yi Ding
Mei-Fan (1 eps)
Allison Smith
Denny (1 eps)
Maureen Flannigan
Mrs. Gamble (1 eps)
Peter Jacobson
Susan's molester (1 eps)
Wendy Phillips
Mrs. Lambright (1 eps)
J.K. Simmons
Gus Loomer (1 eps)
Berlinda Tolbert
Nancy Natarelli (1 eps)
Martin Charles Warner
Mr. Ferguson (1 eps)
Ellen Crawford
Lydia Wright (1 eps)
Kendall Schmidt
Damian (1 eps)
Hallee Hirsh
Rachel Greene (1 eps)
Sunil Malhotra
Lloyd (1 eps)
Madison McReynolds
Hannah (1 eps)
Craig Ricci Shaynak
Fritz (1 eps)
Joe Grifasi
Tom Williams (1 eps)
Rocky Carroll
Mr. Walker (1 eps)
Toni Sawyer
Lucy Kilmer (1 eps)
Allan Kolman
Ed Minyard (1 eps)
Kurt Caceres
Luis Sanchez (1 eps)
Joshua Boyd
Harlin (1 eps)
Kylee Cochran
Terri (1 eps)
Finn Wittrock
Thomas Yoder (1 eps)
Tom Parker
Matt Gilespie (1 eps)
Katya Abelski
Christy (1 eps)
Cesar Flores
Oscar (1 eps)
Mark Valley
Richard Lockhart (1 eps)
Jessica Chastain
Dahlia Taslitz (1 eps)
Casey Boersma
Michael #2 (1 eps)
Dylan Boersma
Michael #1 (1 eps)
Daniel Venegas
Luis (1 eps)
Smalls
Earl (1 eps)
Gedde Watanabe
Yosh Takata (1 eps)
Lulu Antariksa
Anna (1 eps)
Cynthia Ettinger
Linda Pryor (1 eps)
Richard Narita
Ortho #1 (1 eps)
Dinah Lenney
Shirley (1 eps)