Jim Cummings
Darkwing Duck (voice) (91 eps)
Christine Cavanaugh
Gosalyn (voice) (91 eps)
Terence McGovern
Launchpad McQuack (voice) (91 eps)
Dan Castellaneta
Megavolt (voice) (18 eps)
Katie Leigh
Honker Muddlefoot (voice) (16 eps)
Susan Tolsky
Binkie Muddlefoot (voice) (15 eps)
Michael Bell
Quackerjack (voice) (12 eps)
Kath Soucie
Morgana MacCawber (voice) (10 eps)
Tino Insana
Bushroot (voice) (10 eps)
Jack Angel
Liquidator (voice) (7 eps)
Dana Hill
Tank Muddlefoot (voice) (6 eps)
Hamilton Camp
Gizmoduck (voice) (6 eps)
S. Scott Bullock
Tom Lockjaw (voice) (5 eps)
Marcia Wallace
Clovis / Mrs. Cavanaugh (voice) (4 eps)
Susan Silo
Neptunia (voice) (3 eps)
Joey Camen
Stegmutt (voice) (3 eps)
Candi Milo
Lamont (voice) (3 eps)
Teresa Ganzel
Preena Lot (voice) (2 eps)
Danny Mann
J. Gander Hooter (voice) (2 eps)
Jerry Houser
Ham String (voice) (1 eps)
Frank Weed
Eek / Squeak / Archie (voice) (1 eps)
Dani Staahl
Splatter Phoenix (voice) (1 eps)
Victoria Carroll
D-2000 (voice) (1 eps)
Patrick Pinney
The King (voice) (1 eps)
Pat Fraley
Dinosaurs (voice; uncredited) (1 eps)
Ron Feinberg
Vladimir Goudenov Grizzlikoff / Angry Citizen / Sailor (voice) (1 eps)
Robert Ito
Goose Lee (voice) (1 eps)
Hal Rayle
Museum Curator / Ninja (voice) (1 eps)
Charlie Adler
Loophole (voice) (1 eps)
Brian Cummings
(voice) (1 eps)
Brian George
(voice) (1 eps)
Barry Gordon
Dr. Fossil (voice) (1 eps)
Nancy Linari
Shyster (voice) (1 eps)