Gerald Anderson
Benjamin "Budoy" Maniego/Dizon (110 eps)
Jessy Mendiola
Jacqueline "Jackie" Marasigan-Maniego (110 eps)
Enrique Gil
Benjamin "BJ" Maniego/Dimalanta/Chavez (110 eps)
Janice de Belen
Elena Dizon (110 eps)
Zsa Zsa Padilla
Luisa Maniego (110 eps)
Christian Vasquez
Dr. Isaac Maniego (110 eps)
Mylene Dizon
Dr. Grace Maniego (110 eps)
Barbara Perez
Dr. Alberta Maniego (110 eps)
Dante Rivero
Renato Dizon (110 eps)
