Isolda Dychauk
Lucrezia Borgia (39 eps)
John Doman
Rodrigo Borgia (38 eps)
Mark Ryder
Cesare Borgia (38 eps)
Assumpta Serna
Vannozza Catanei (38 eps)
Marta Gastini
Giulia Farnese (38 eps)
Sarah Stern
Jeanne de Berry (26 eps)
Andrea Sawatzki
Adriana de Mila (24 eps)
Stanley Weber
Juan Borgia (24 eps)
Diarmuid Noyes
Alessandro Farnese (24 eps)
Art Malik
Francesc Gacet (24 eps)
Christian McKay
Cardinal Sforza (24 eps)
Dejan Čukić
Guiliano Della Rovere (24 eps)
Rafael Cebrian
Rodrigo Borgia Lanzol (14 eps)
Alejandro Albarracín
Alfonso di Calabria (14 eps)
Babsie Steger
Giovanna Farnese (14 eps)
Quentin Faure
Jean de Foix (14 eps)
Marc Pickering
Ippolito d'Este (6 eps)
Elisa Mouliaá
Pantisilea (5 eps)
Dave Legeno
Guidobaldo de Montefeltro (4 eps)
Daisy Lewis
Maria Diaz Garlon (2 eps)
Laura Fedorowycz
SILVIA RUFFINI (1 eps)
Wilf Scolding
Anton van Lalaing (1 eps)
Marco Calvani
Christoforo Castanea (1 eps)
Eliška Křenková
Sancia Squillace (1 eps)
Amber Rose Revah
Maacah Bat-Talmai (1 eps)
Maacah Bat-Talmai
Sancia Squillace (1 eps)
Monica Lopera
Maria Enriques de Luna (1 eps)
Lucia Edwards
Female Pelgrim (1 eps)