Steve Buscemi
Enoch 'Nucky' Thompson (12 eps)
Michael Pitt
James 'Jimmy' Darmody (12 eps)
Gretchen Mol
Gillian Darmody (12 eps)
Kelly Macdonald
Margaret Schroeder (12 eps)
Michael Shannon
Nelson Van Alden (12 eps)
Shea Whigham
Elias 'Eli' Thompson (12 eps)
Aleksa Palladino
Angela Darmody (12 eps)
Michael Stuhlbarg
Arnold Rothstein (12 eps)
Stephen Graham
Al Capone (12 eps)
Charlie Cox
Owen Slater (12 eps)
Paz de la Huerta
Lucy Danziger (12 eps)
Michael Kenneth Williams
Albert 'Chalky' White (12 eps)
Dabney Coleman
Commodore Louis Kaestner (12 eps)
Kevin Carolan
Boardwalk Barker (12 eps)
Greg Antonacci
Johnny Torrio (12 eps)
Vincent Piazza
Charles 'Lucky' Luciano (12 eps)
Meg Chambers Steedle
Billie Kent (12 eps)
Patrick Kennedy
Dr. Douglas Mason (12 eps)
Anatol Yusef
Meyer Lansky (12 eps)
Chris Caldovino
Tonino Sandrelli (12 eps)
Skai Jackson
Adeline White (12 eps)
Julianne Nicholson
Esther Randolph (12 eps)
Jonathan Dickson
Delivery Guy (1 eps)