Kelly Reilly
Dr. Catherine Black (13 eps)
Ditch Davey
Dr. Ian Bickman (13 eps)
David Ajala
Will Van Renseller (13 eps)
Ali Wong
Dr. Lina Lark (13 eps)
Laura Fraser
Regan Black (13 eps)
David Chisum
Joshua Black (13 eps)
Siobhan Williams
Esme Black (13 eps)
Terry Kinney
Dr. Owen Morely (13 eps)
Vanessa Redgrave
Dr. Hartramph (13 eps)
Aja Naomi King
Ali Henslee (8 eps)
Sawyer Barth
Young Joshua Black (3 eps)
Emma Ishta
Cara (1 eps)
Arian Moayed
Cyrus (1 eps)
Tom Pelphrey
Joseph Moran (1 eps)
Trini Alvarado
Beatrice King (1 eps)
Tasso Feldman
Leo Robinson (1 eps)
Audrey Esparza
Carlotta (1 eps)
Peter Maloney
Harry (1 eps)
Michael Pemberton
Lionel Stark (1 eps)
David Rasche
Hunter Black (1 eps)
Brendan Griffin
Young Hunter (1 eps)
Joel Perez
Mexican Carson (1 eps)