Tara Strong
Ben Tennyson (voice) (13 eps)
Meagan Moore
Gwen Tennyson (voice) (13 eps)
Paul Eiding
Grandpa Max (voice) (13 eps)
Dee Bradley Baker
Stinkfly / Wildmutt (voice) (13 eps)
Steve Blum
Ghostfreak / Heatblast / Vilgax (voice) (13 eps)
Richard McGonagle
Four Arms (voice) (13 eps)
Fred Tatasciore
Cannonbolt / Ripjaws (voice) (13 eps)
Richard Steven Horvitz
Grey Matter (voice) (13 eps)
Jim Ward
Diamondhead / Wildvine / XLR8 (voice) (13 eps)
Charlie Schlatter
Kevin Levin (voice) (3 eps)
Khary Payton
Hex (voice) (2 eps)
Kari Wahlgren
Grey Matter Gwen (voice) (2 eps)
Vanessa Marshall
Diamond Head Gwen / Four Arms Gwen (voice) (2 eps)
Tom Kane
Ultimos (voice) (2 eps)
Kath Soucie
Little Boy / Tiffany (voice) (2 eps)
Robert Patrick
Phil (voice) (1 eps)
Cree Summer
Frightwig (voice) (1 eps)
Jeff Doucette
Thumbskull (voice) (1 eps)
Dwight Schultz
Dr. Animo (voice) (1 eps)
Richard Doyle
Enoch (voice) (1 eps)
Robert Picardo
Leader Alien (voice) (1 eps)
James C. Mathis III
Enforcer Alien (voice) (1 eps)
Michael Gough
Lt. Steel (voice) (1 eps)
Bill Ratner
The Seer (voice) (1 eps)
Grey DeLisle
Heatblast Gwen (voice) (1 eps)
Jack Angel
Technorg (voice) (1 eps)
Armin Shimerman
Slix (voice) (1 eps)
Greg Ellis
Synaptak (voice) (1 eps)
John DiMaggio
Vulkanus (voice) (1 eps)
Jennifer Hale
Gilbert / Mandy (voice) (1 eps)
Kim Mai Guest
Andy (voice) (1 eps)
Patricia Lentz
Mildred / Gypsy (voice) (1 eps)
Dave Wittenberg
Harold / Escape Artist / Emcee (voice) (1 eps)