Grey DeLisle
Daphne Blake (voice) (55 eps)
Frank Welker
Fred Jones / Scooby-Doo (voice) (54 eps)
Matthew Lillard
Shaggy Rogers (voice) (53 eps)
Kate Micucci
Velma Dinkley (voice) (53 eps)
Mark Hamill
General Stall (voice) (1 eps)
Chord Overstreet
Mitchell / Andrew (voice) (1 eps)
JB Blanc
Vic / Colander (voice) (1 eps)
Ben Diskin
Additional Voices (voice) (1 eps)
David Kaye
Bradwick / Headless Count (voice) (1 eps)
Julie Nathanson
Kimmy / Bride’s Mother (voice) (1 eps)
Laraine Newman
Professor Salazar / Running Girl / Female Security Guard (voice) (1 eps)
Dee Bradley Baker
Professor / Sobek / Duncan (voice) (1 eps)
Kiff Scholl
Jeff / Male Security Guard (voice) (1 eps)
Edward Bosco
Werewolf (voice) (1 eps)
Christian Lanz
Miguel (voice) (1 eps)
Candi Milo
Ms. Tuckle (voice) (1 eps)
Phil Morris
Dunsbury (voice) (1 eps)
Liliana Mumy
Daughter (voice) (1 eps)