Hilary Swank
Emma Green (10 eps)
Mark Ivanir
Misha (10 eps)
Ray Panthaki
Ram (10 eps)
Vivian Wu
Yu (10 eps)
Ato Essandoh
Kwesi (10 eps)
Talitha Bateman
Alexis Logan (10 eps)
Josh Charles
Matt Logan (10 eps)
Felicia Patti
Cassie Ramirez (7 eps)
Gabrielle Rose
Darlene Cole (7 eps)
Fiona Fu
CNSA Head / Li Jun (7 eps)
Martin Cummins
Jack Willmore (6 eps)
Brian Markinson
George Lane (6 eps)
Michael Patrick Thornton
Dr. Fred Putney (5 eps)
Diana Bang
Freddie (5 eps)
Veena Sood
IRSO Head Meera Patel (5 eps)
Sharmaine Yeoh
Chinese Translator (4 eps)
Alex Vishniakoff
Roscosmos Sergei Sokolov (4 eps)
John Murphy
Ryan Masters (4 eps)
Nadia Hatta
Mei Chen (3 eps)
Alessandro Juliani
Dr. Lawrence Madigan (3 eps)
Donald Sales
Jerry (3 eps)
Ryan Mah
Dave (3 eps)
Jay Zhang
Zhang Yong (3 eps)
Olena Medwid
Natalya Popov (3 eps)
Adam Pateman
Adam (3 eps)
Derrick Su
Zhang Lei (3 eps)
Jamie Nieto
Travis Parker (3 eps)
Krista Magnusson
Engineer #5 (3 eps)
Jessica Garcie
NASA Assistant (3 eps)
Lydia Campbell
Jane (3 eps)
Anthony Ingram
ESA Head Ted Salter (3 eps)
Liza Cosier
Russian Translator (2 eps)
Marion Eisman
Miriam Weisberg (2 eps)
Emma Sukhomenyuk
Misha's Grandchild #1 (2 eps)
Maxim Aleksandrov
Misha's Grandchild #3 (2 eps)
David Pavlov
Misha's Grandchild #2 (2 eps)
Lisa Chandler
Engineer #4 (2 eps)
Bethel Lee
Engineer #6 (2 eps)
Rachel Maddow
Rachel Maddow (1 eps)
Michael J. Massimino
Self (as Mike Massimino) (1 eps)
Requell Jodeah
BBC Reporter (1 eps)
Uri Burstyn
Russian Reporter (1 eps)
Bowen Zhang
Chinese Reporter (1 eps)
Anoop Randhawa
Another Reporter (1 eps)
Sasha Piltsin
GNC Operator (1 eps)
Quynh Mi
SATCOM Operator (1 eps)
Kris McRonney
INCO Operator (1 eps)
Carly Buhler
THOR Operator (1 eps)
Aidan Wang
SURGEON Operator (1 eps)
Heather Decksheimer
Operator (1 eps)
Ian Hawes
ESA Engineer (1 eps)
Bruce Dawson
Hutch Fulton (1 eps)
Dominika Pavlova
Young Natalya (1 eps)
Bonnie Hay
Nurse (1 eps)
Sonia Sunger
Newscaster (1 eps)
Anastassia Krainik
Anna Popov (1 eps)
Rhys Fleming
Annie (1 eps)
Rocky Anderson
Texan (1 eps)
Bernie Yao
Gordon (1 eps)
Anantjot S Aneja
Rohit Arya (1 eps)
Krish Marwah
Young Ram (1 eps)
Ava Julien
Teacher (1 eps)
Gabriela Reynoso
Marie Rodriguez (1 eps)
Kamal Sidhu
Ram's Mother (1 eps)
Gary Sanghera
Doctor (1 eps)
Javier Lacroix
Priest (1 eps)
Alona Tal
Miriam Weisberg (1 eps)
Aiden Stoxx
Kwesi Weisberg-Abban - Young (1 eps)
Adrian Deheer-Amissah
Kwesi Weisberg-Abban - 18yo (1 eps)
Sean Kuling
Scott (1 eps)
Madeleine Kelders
Doctor (1 eps)
Bobby Hernandez
Instructor (1 eps)
Michael Benefield
Crew Assist (1 eps)
Daniel Martin
Engineer #2 (1 eps)
Aliana Cerullo
15-Year-Old Emma Green (1 eps)
Clem Cheung
Lu's Father (Older) (1 eps)
Irene Tsu
Lu's Mother (Older) (1 eps)
Wade Sun
Husband (Young Lu's Father) (1 eps)
Jessie Liang
Woman (Young Lu's Mother) (1 eps)
Vincent Cheng
Doctor (1 eps)
Felicia Patti
Cassie Ramirez (1 eps)
Shevon Nieto
Veronica (1 eps)
Grace Wang
CNSA Assistant (1 eps)