Kathy Bates
Agnes Mary Winstead / Thomasin 'The Butcher' White (10 eps)
Sarah Paulson
Audrey Tindall / Shelby Miller / Lana Winters (10 eps)
Cuba Gooding Jr.
Dominic Banks / Matt Miller (10 eps)
Lily Rabe
Shelby Miller (10 eps)
André Holland
Matt Miller (10 eps)
Denis O'Hare
Elias Cunningham (10 eps)
Wes Bentley
Ambrose White / Dylan (10 eps)
Evan Peters
Rory Manahan / Edward Philippe Mott (10 eps)
Cheyenne Jackson
Sidney Aaron James (10 eps)
Angela Bassett
Monet Tumissee / Lee Harris (10 eps)
Chelsea Alden
Alissa (3 eps)
Lady Gaga
Scáthach (3 eps)
Finn Wittrock
Jether Polk (2 eps)
Taissa Farmiga
Sophie Green (1 eps)
Jon Bass
Milo (1 eps)
Jacob Artist
Todd Connors (1 eps)
Emma Bell
Tracy Logan (1 eps)
James Morosini
Bob Kinneman (1 eps)